癌症症狀與其積極性治療和健康相關生活品質密切相關，因此青少年健康相關生活品質經常是臨床醫療與癌症研究的重要預測指標。本研究目的為探討癌症青少年的健康相關生活品質及其相關因素。研究設計採橫斷式調查法，研究對象來自兩家醫學中心的120位癌症青少年病患。研究工具包括台灣版SF-36建康評估量表、台灣版安德森症狀評估量表與身體生理功能狀態量表等三部分。研究結果發現：一、癌症青少年身體生理功能角色受限面向之健康相關生活品質得分最低，身體疼痛面向之健康相關生活品質得分最高；二、治療組健康相關生活品質平均得分低於完成治療組，並且呈現顯著性差異；三、低身體生理功能狀態與低血素值癌症青少年的健康相關生活品質得分愈低；四、年齡愈大其健康相關生活品質得分愈低，在性別間則無顯著差異。本研究可增進癌症青少年病患健康相關生活品質之了解，藉以發展合宜的介入措施外，並可進一步支持台灣版SF-36健康評估量表應用於台灣癌症青少年之通用性，以協助監測癌症青少年於癌症治療期間與定期追蹤過程之健康相關生活品質。

Cancer-related symptoms are closely linked to quality of life. The health-related quality of life（HRQoL） is an important outcome for clinical cancer care and oncology research in adolescent cancer survivors. The purpose of this study was to examine HRQoL in adolescents with cancer. With a cross-sectional design, 120 adolescent with cancer were recruited from two medical centers using the SF-36 HRQoL, the M. D. Anderson Symptom Inventory, and Karnofsky Performance Scale. Major finding: 1.The role-physical domain of HQoL received the lowest score in adolescent cancer patients, and bodily pain domain of HQoL received the highest score. 2. Adolescence who were receiving cancer treatment had significantly poorer HRQoL than the off-treatment group. 3. The health-related quality of life Mean scores were significantly positively correlated with performance status and hemoglobin levels. 4. Older survivors showed a lower levels of HRQoL.
The results from this study assist clinicians better understanding the status of quality of life and provide important
implications in promoting quality of life for adolescents with cancer.