目的：代謝症候群為心血管危險因子的集合，以預防醫學的角度應對代謝症候群進行早期診斷及治療。本研究即針對某醫學中心員工進行代謝異常症候盛行率及其相關因子分析。方法：以橫斷性研究設計，利用台北某醫學中心2007年員工健康檢查資料，進行代謝症候群流行病學分析。代謝症候群判定是依照2007年衛生署所修改的新標準，因體檢結果的限制，以總膽固醇取代高密度脂蛋白膽固醇。結果：在1203名受檢者中，代謝症候群盛行率為16.3%(男性為24.8%，女性為11.7%)；代謝症候群異常指標組成，以中央型肥胖合併血壓過高及膽固醇總量過高比例最高；以多項式邏輯斯迴歸分析發現，與代謝症候群指標1-2項有關因子包括性別(男vs女，勝算比(odds ratio, OR)：1.85、95%信賴區間(confidenceinterval, CI)：1.28-2.70)、年齡(OR: 1.04, 95%CI: 1.02-1.06)、及肥胖(有vs無，OR: 1.39,95%CI: 1.31-1.47)；與符合代謝症候群指標3-5項有關的因子亦包括性別(男vs女，OR: 2.08,95%CI: 1.28-3.45)、年齡(OR: 1.12、95%CI: 1.09-1.14)、及肥胖(有vs無，OR: 1.73, 95%CI:1.60-1.87)。結論：健康促進醫院的推廣建議優先控制腰圍與體重以預防代謝症候群。

Objectives: Metabolic syndrome is a cluster of cardiovascular risk factors. From the viewpointof preventive medicine, it is essential for early diagnosis and appropriate treatment to subjects withmetabolic syndrome. The objective in this study is to explore the prevalence and associated riskfactors of metabolic syndrome among hospital staff based on the health examination. Methods:Based on the cross-sectional study design, the database of the health examination of the workersin a medical center on the northern Taiwan is analyzed. The definition of metabolic syndrome isaccording to the criteria proposed by Department of Health in 2007, Taiwan. Due to the limitation ofthe examination, the total cholesterol is used to replace the HDL-C value. Results: The prevalenceof metabolic syndrome is 16.3%(24.8% in male and 11.7% in female) among 1203 screened subjects.The highest proportion of abnormal index of metabolic syndrome is central obesity combinedwith higher blood pressure and total cholesterol. Based on the multinomial logistic regression, thesignificant factors related to 1-2 abnormal index of metabolic syndrome include gender (male vsfemale, OR=1.85, 95%CI: 1.31-1.47), age (OR=1.04, 95%CI: 1.02-1.06) and obesity (OR=1.39,95%CI: 1.31-1.47). In addition, the significant factors related to 3-5 abnormal index of metabolicsyndrome also include gender (male vs female, OR=2.08, 95%CI: 1.28-3.45), age (OR=1.12,95%CI: 1.09-1.14) and obesity (OR=1.73, 95%CI: 1.60-1.87). Conclusion: To promote the healthpromoting hospital, the priority of metabolic syndrome prevention is controlled waist circumferenceand body weight.