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內科學誌 Scopus

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篇名 原發性肝臟血管肉瘤 –中部某醫學中心十年的經驗
卷期 22:6
並列篇名 Primary Hepatic Angiosarcoma –10-year Experience in A Single Medical Center in Middle Taiwan
作者 施凱倫顏旭亨蘇維文吳順生孫茂勝林國川陳志榮
頁次 423-430
關鍵字 肝臟(Liver)血管肉瘤(Angiosarcoma)治療(Treatment)預後(Prognosis)ScopusTSCI
出刊日期 201112

中文摘要

原發性肝臟血管肉瘤是相當罕見的肝臟惡性腫瘤,只占肝臟惡性腫瘤的1%左右。本研究分析從民國90 年1 月到民國99 年12 月,在彰化基督教醫院診斷罹患此癌症的10 位個案。本研究發現,罹患此腫瘤的病人多以老年人和男性居多,右上腹痛和貧血是最常見的表現。雖然肝外轉移的情況不常見,但是多數病人發現時,腫瘤已經廣泛的侵襲肝臟組織,而使得此疾病的預後極差。影像學表現是決定病人預後重要的工具,若是在電腦斷層上看到腫瘤已經侵犯肝臟兩葉或是有腹水,病人多存活不到3 個月。即使腫瘤一開始只侵犯肝臟單葉而接受開刀治療,術後肝內轉移仍舊很快發生,形成臨床治療上重大和困難的挑戰。

英文摘要

Primary hepatic angiosarcoma is a rare hepatic malignant tumor,accounting for only 1% of all primary liver malignancy. This study retrospectively analyzes the 10 patients of hepatic angiosarcoma in Changhua Christian hospital from 2001, January to 2010, December. This study shows the tumor happens in elders and male prominently and the initial presentation is abdominal pain and anemia. Extra-hepatic metastasis are unusual,however, most patients have tumors involvement in liver extensively and with very poor prognosis. Image study is an important tool to determine the prognosis of the patients and if tumors involvement in bilateral liver lobes or ascites seen in computer tomography, the patient's survival duration usually less than 3 months. Even patients received lobectomy if single liver lobe involvement of tumor is found initially, intra-hepatic metastasis usually develop soon. The treatment of this malignancy is a great and difficult clinical challenge.

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