痛風之名，始於金元時代醫家李東垣，詳論於朱丹溪，當時丹溪封於痛風的定羲是四肢百節走痛，是廣羲的關節疾病，古多以痺證、白虎、歷節風名之，而現代醫學之痛風，則系專指嘌吟代謝紊亂，高尿酸血症所引發的“痛風性關節炎”，所以病名雖同，定羲則異。丹溪論痛風，提出了痰、風熱、風灦、血虛等病因，並認爲血虛火盛，血熱瘀凝爲痛風證病的主要病機，故治療上主辛熱之劑流散寒濕以治其標，以養血清熱以治其本，並創製二妙散，上中下通用痛風丸等著名方劑。

The name of disease pattern "Tong-feng" was mentioned firstly by Li-Dong-Yuan, who was a physician at Jin-Yuan Dynasty in China. The treatment of Tong-feng zheng was detail discussion by Dan-Xi Ju. The definition of Tong-Feng zheng by Dan-Xi’s concept was arthralgia in extremities. It is a broad meaning of joint disease. In ancient age, Tong-Feng zheng had an another names of Bi-Zheng or white tiger or joint-running wind. The modern medicine, the name of "gout" is purine metabolism disturbance which induced gouty arthritis resulted from hyperuricaemia. The Chinese word of Tong-feng zheng is the same as gout, but both the definition is different. Ju's thinking process that the etiology of Tong feng zheng resulted from phlegm, wind-heat, wind-dampness and blood vacuity. He though that blood vacuity and fire preponderance as well as blood heat with stasis were main mechanism of Tong-feng zheng attack. He used the acrid hot herbs to expelling cold-damp and used the way of nourishing the blood and clearing heat to treat the main cause. On the other hand, he created some famous formulas of Er-Miao San and Shang-JungShia Tong Feng Wan etc.