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中華民國泌尿科醫學會雜誌

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篇名 電流汽化攝護腺時組織導電性的測定
卷期 11:2
並列篇名 Measurement of Tissue Conductivity During Electrosurgical Vaporization of the Prostate
作者 邱文祥張心湜謝一紅池春蓮楊順聰
頁次 056-061
關鍵字 攝護腺電燒汽化導電性prostateelectrosurgical vaporizationconductivityTSCI
出刊日期 200006

中文摘要

在吾人先期發表之研究中,已證實當傳統電繞刀接觸攝護腺腺體及包膜時會產生不同之組織導電性。而最近所發展出之經尿道攝護腺汽化手術,主要是利用交流電傳導過一溝狀之銀鎳滾輪,藉著滾輪表面產生之高熱,將攝護腺組織直接汽化。此種裝置與傳統環狀電燒刀不同,是否亦會有類似的電流傳導現象,仍不得而知。吾人即擬利用先前之研究模式來測量攝護腺接受汽化手術時,不同組織產生之導電性。我們設計了兩步驟之實驗來探討此問題。首先利用豬肉來模擬攝護腺不同組織,其中肌肉類似攝護腺腺體組織,脂肪類似攝護腺旁脂肪,皮膚類似攝護腺包膜。在電壓為150W、220W及280W下分測其輸出電流大小,進而分析其差異。結果發現當汽化滾輪接觸脂肪時,因電阻最大所以產生之電流最小,而皮膚所產生之電流居中,而當滾輪接觸豬肉肌肉時所產生之電流最大,此三者之差異皆具有統計學意義。在狗活體實驗方面,我們用30~40公斤的雜種公狗為動物模式。汽化滾輪在220W下分別接觸攝護腺組織、尿道、攝護腺包膜及攝護腺旁脂肪。結果顯示攝護腺體之輸出電流最大,為0.924±0.337安培(A),尿道及包膜之輸出電流次之,分別為0.799±0.304安培(A)及0.805±0.401安培(A),而攝謢腺旁脂肪其電流最小0.686±0.332安培(A)。以上數據在統計學亦具顯著差異(n=8,p<0.005)。由以上兩項實驗結果顯示,不管電流是以何種方式接觸組織,通過不同組織均會產生不同的導電性。吾人即擬利用此特性,在臨床手得時以自動斷電裝置控制電流,一旦汽化滾輪接觸攝護腺包膜時旋即斷電。如此即可能避免手術中攝護腺包膜之破裂及其引起之併發症。

英文摘要

An experimental model established by the authors has documented that different tissue conductivity was generated when the traditional cutting loop contacted the prostatic adenoma and capsule. Recently, the electrosurgical vaporization technology was used to treat benign prostatic hyperplasia. High temperature generated on the surface of the grooved silver nickel electrodes enables direct vaporization of the prostate. The authors thereafter attempted to measure different tissue conductivity during electrosurgical vaporization of prostatic tissues. This study was composed of two parts, in-vitro pork and in-vivo canine experiments. The first part of the study utilized a block of pork to measure the tissue conductivity when the vaporizing electrode with different power (150W, 220W and 280W) contacted skin, subcutaneous fatty and meat respectively. The results showed that subcutaneous fatty tissue, (like periprostatic fatty tissue) generated the lowest conductivity because of its highest tissue resistance. The meat (like prostatic adenoma) has the highest conductivity, and the skin (like prostatic capsule) has conductivity in between. These differences all showed statistical significance. The second part of the study enrolled ten mature mal dogs weighted 34-40 kgs to measure tissue conductivity when the electrode contacted different prostatic tissues at the power of 220W. Output dignals on ureghra mucosa was 0.799±0.304 Ampere (A), on prostatic tissue was 0.924±0.337 A, on prostatic capsule was 0.805±0.401 A, on periprostatic fatty tissue was 0.686±0.332 A, all p values were less than 0.05 (paired t-test). It appeared the periprostatic fatty tissue has the lowest tissue conductivity followed by the prostatic capsule and the prostatic adenoma.

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