篇名 | Urinary Nephrogenic Adenoma |
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卷期 | 15:2 |
並列篇名 | 泌尿道的腎性腺瘤 |
作者 | 蔡秉儒 、 余家政 、 李瀛政 、 黃榮慶 |
頁次 | 065-068 |
關鍵字 | 腎性腺瘤 、 腺性化生 、 Adenomatous metaplasia 、 Urinary nephrogenic adenoma |
出刊日期 | 200406 |
研究目的:腎性腺瘤在泌尿道是一種少見的良性腫瘤,也是泌尿上皮細胞的腺性化生。其發生的原因尚非十分清楚。我們發表此疾病的特徵,病因探討,及治療方法。材料與方法:我們從1990年11月到2002年4月,以回溯法去尋找本院曾患有腎性腺瘤的病患。有5個病患被發現,並參考其其他相關主題的文章。結果:這5位病患,有2位是發生於膀胱,3位是發生於輸尿管。慢性發炎,尿路結石及輸尿管狹窄是其發生的相關原因。對膀胱處的病兆,經尿道腫瘤切除手術被執行。而輸尿管的病兆,局部輸尿管切除及再吻合手術被執行。這些病患術前的診斷是有困難的。組織學看起來像似腎臟的集尿系統上皮,由一層的立方上皮所組成。平均追蹤是66.6月(從13個月到111個月)。追綜結果並無復發的情形發生。結論:泌尿的腎性腺瘤是一種少見的良性病兆,不應被視為前惡性變化。局部的外科切除是足夠的。
Objective: Nephrogenic adenomas are rare lesions of the urinary tract. Their etiology is entirely unclear. We present the character, etiology, and treatment of urinary nephrogenic adenomas from our own experiences. Materials and Methods: We retrospectively reviewed the charts of patients with urinary nephrogenic adenomas from November 1990 to April 2002 in our hospital. Five cases of urinary nephrogenic adenoma were encountered, and their medical records were reviewed. Results: Of these 5 nephrogenic adenomas, 2 were found in the urinary bladder, and the other 3 were in the ureter. Chronic inflammation, urolithiasis, and ureteral stricture were the associated conditions. Transurethral resection of the bladder tumor was performed for the bladder lesions. Segmental resection with reanastomosis was performed for the ureteral lesions. The impressions in those cases were ureteral stones with ureteritis, ureteral stricture with hydronephrosis, vesical stones, and chronic cystitis. None was accurately diagnosed preoperatively. The histology resembled primitive renal collecting tubules as edematous papillary projections lined by a single layer of cuboidal epithelial cells in the lamina propria. The mean follow-up period was 66.6 (range, 13 to 111) months. Their outcomes were good with no evidence of recurrence. Conclusions: Nephrogenic adenomas of the urinary tract are rare benign lesions and should not be viewed as a premalignancy. Surgical intervention with limited resection is appropriate.