背景: 泌尿道感染為最常見的細菌感染性疾病，可發生在所有的年齡層，病人臨表徵為解尿困難、頻尿、解尿灼熱感或上恥骨部(膀胱)不舒服等。本研究主要探討自動尿液沉渣分析儀UF-1000i對於臨床檢體在細菌計數與細菌培養之相關性，以及泌尿道感染早期診斷之應用。方法：100年9月1日至100年11月30日，收集就診病人送檢尿液培養之檢體共 204人，196人為有效檢體(96%)，先進行尿液培養後再以自動尿液沉渣分析儀UF1000i 進行尿液分析，探討其再現性與相關性。結果：UF-1000i 與手工菌量檢查相關性佳(AOC=0.93)。目前細菌CLSI規範切點為
100/uL 時，此方法之敏感性 87.5%，特異性 85.1%，為相關性表現極佳之方法。當切點分
別在 >=1uL、>=10uL、>=100uL，其敏感性/特異性分別為：93.4%/22.7%、92.5%/64.3%、
87.5%/85.1%，為相關性極佳之方法。泌尿道感染高度關切病人切點在 >=1uL、>=10uL、
>=100uL，其敏感性/特異性分別為：100.0%/14.3%、100.0%/33.3%、93.3%/60.7%，在泌尿
道感染高度關切病人可做為篩選方法，接近100%之敏感度。結論：UF-1000i全自動尿液沉渣分析結果可快速提供臨床診斷數據，幫助泌尿道感染早期診斷，並給予患者適當之治療，也可以減少醫療資源的浪費。

Background: The urinary tract infection is the most common bacterium infectious disease,may occur in all age groups, the characterizations of patient are dysuria, frequency, burning sensation when urination, or lower abdomen discomfort and so on. This research discuss the fully automated urine analyzer UF-1000i for the correlation the clinical test sample in bacterium counting and the urine culture, as well as application of the urinary tract infection early diagnosis.Methods: From September 1, 2011 to November 30, 2011, the collection of patient’s
specimens of total 204, of which 196 were valid samples. The effectiveness was 96%. We performed the urine culture and then carried on the urine analysis by the fully automated urine analyzer UF-1000i to discuss its reproducibility and relevance. The measurement of the current
manual method has excellent correlation.Results：The correlation of the UF-1000i and manual bacterium quantity examine is good (AOC=0.93).
According to the bacterial CLSI standard method, cut-off value is 100/uL, sensitivity is 87.5%, specificity is 85.1%, it’s performance of relevance is excellent. When the cut-off value in ≧1uL 、≧10uL 、≧100uL, its sensitive/specificity respectively is: 93.4/22.7%,92.5/64.3%, 87.5/85.1%. The cut-off value of highly suspected urinary tract infection patients in
≧1uL,≧10uL, ≧100uL, its sensitive/specificity respectively is:
100.0/14.3%, 100.0/33.3%,93.3/60.7%.It is possible highly to do the
screening methods with close 100% sensitivity nearly.Conclusion: The Fully Automated Urine Analyzer UF-1000i can provide faster clinical data
to help early diagnosis of urinary tract infection, and give the patient the adequate treatments earlier. The procedures also reduce the waste of the medical resources.