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臺灣應用輻射與同位素雜誌

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篇名 使用聚合膠片及丙胺酸劑量計量測血品照射儀之劑量分布比較及品質保證
卷期 8:2
並列篇名 Comparison of Dose Distribution of Blood Irradiator by Using EBT Films and Alanine Dosimeter and Quality Assurance
作者 陳合興蔡秋聲張瑞旺謝獻旭林進清陳怡婷李家誠
頁次 277-282
關鍵字 血品照射儀劑量分布EBT 膠片丙胺酸劑量計品質保證blood irradiatordose distributionEBT filmAlanine dosimeterQuality Assurance
出刊日期 201206

中文摘要

血品照射儀為輸血前對輸血血品照射一定程度劑量的放射線儀器,在國內已漸漸取代傳統使用直線加速器或鈷-60 遠隔治療機來執行血液照射作業,目的在輸血前以放射線將血液成份中會造成輸血後移植物反宿主反應的T 細胞淋巴球去活化,在劑量量測中將使用聚合膠片和核能研究所提供的丙胺酸劑量計,兩者皆照射臨床使用劑量25 Gy,將量測結果進行二維劑量分布比較,在丙胺酸劑量計最大劑量為29.33 Gy,最小劑量為23.32 Gy,平均劑量為26.6±2.04 Gy,聚合膠片所量測的最大劑量為28 Gy,最小劑量為21.5 Gy,平均劑量為25±2.45 Gy,丙胺酸劑量計和聚合膠片兩者的上、下端劑量皆小於等於中間劑量,左、右端劑量皆大於中間劑量,兩者結果比較最大差異為5.06%,其結果皆符合血品照射儀的劑量限值,本研究使用之劑量技術可使用於例行品保作業有效測知血品照射儀之功能異常,做及時之修正確保劑量之正確性,可供其他有此需求的醫院作為參考,以滿足臨床應用之需求。

英文摘要

In order to inactivate the T-cell lymphocytes, we always use radiation to expose blood bags. Because T-celllymphocytes may cause Graft-versus-Host Disease (GVHD) in some patients with AIDS or cancer. Many years ago, it isgeneral method to irradiate blood bags by using linear accelerator or Cobalt-60 tele-therapy machine. Recently, linac orCobalt-60 tele-therapy machine are replaced by blood irradiator. The aim of this study is to use EBT film and alaninedosimeter to measure radiation dose irradiated from the blood irradiator and evaluate their performance. EBT films andalanine dosimeter were irradiated 25 Gy. The results were compared in 2-D dose distribution. The maximum dose are29.33Gy and 28.0Gy, minimum dose are 23.32 Gy and 21.5 Gy, mean dose are 26.6±2.04 Gy and 25±2.45 Gy in EBTfilm and alanine dosimeter, respectively. In results, the bottom dose of 2D dose distribution in alanine dosimeter and EBTfilm are less than o equal the mean doses. The left and right end doses were greater than the mean dose. The difference oftwo dosimeters was 5.06%. The radiation dose which measured by EBT and alanine dosimeter represented dosagereleased by the blood irradiator was within effective range to inactivate the T-cell lymphocytes. We conclude EBT filmsare as effective as alanine dosimeter in measuring dose of radiation by blood irradiator.

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