本文簡介兒童與青少年代謝症候群的機制1診斷標準、預防和介入口代謝症候群是指含肥胖及血脂異常、血糖代謝異常及高血壓相關共病症的集合症狀，與糖尿病及心血管疾病密切相關口受種族、年齡及發展的影響，至今全球對兒童及青少年代謝症候群仍無一致的診斷標準口胎兒時期的母體子宮環境、懷孕母體營養過多或不足、兒童及青少年的過度營養及身體活動量下降都是造成代謝症候軒的重要因素。學者建議改變生活型態、減重來控制代謝症候群的危險因子，加以預防及治療。目前研究顯示生活型態介入對代謝症候群有良好效果，唯仍骯乏較高證據等級之隨機控制研究的支持。(物理治療2012;37(2): 104-113 )

The purpose of this review was to discuss the mechanism, diagnostic criteria, prevention, and clinical intervention for children and adolescents with metabolic syndrome. Metabolic syndrome is a group of risk factors which closely related to cardiovascular diseases and diabetes mellitus. Obesity, dyslipidemia, impaired glucose metabolism, and elevated blood pressure constitute the components of metabolic syndrome. Ethnicity as wel1 as age and developmental processes have influential effects on metabolic risk factors. There is no consensus on the diagnostic criteria with worldwide acceptance for metabolic syndrome among this population. The environment for uterine fetal development, ovec- or under-nourishment of the pregnant mother, and overnutrition and/or decreased physical activity in childhood may lead to the metabolic syndrome in children. Lifestyle intervention, weight loss and reduction of metabolic risk factors are reCOffimended as prevention measures and as the main treatment goal for children and adolescents with metaboJic syndrome. Although lifestyle intervention has been shown to have beneficial effects in several clinical trials, more well-designed randomized control1ed trials are required in the future. (FJPT 2012;37(2): 104-113)