背　景　生活品質在精神照護上是重要的議題，但是對精神分裂症病患之污名感受、污名因應與生活品質之相關研究仍有限。
目　的　探討精神分裂症病患之污名感受、污名因應與生活品質之相關。
方　法　採橫斷式、相關性研究設計，以「基本屬性」、「污名感受量表」、「污名因應取向量表」、「台灣簡明版世界衛生組織生活品質問卷」收集資料。共收案119位精神分裂症病人，所得資料以SPSS12.0 for Windows套裝軟體進行統計分析。
結　果　⑴研究對象生活品質指標得分62.40，屬中等程度；⑵工作時數較長者、有復健工作者、及有領補助金者生活品質較差；⑶在整體生活品質影響方面，婚配阻礙因素最高，採隱藏保密取向因應，生活品質感受較佳；⑷領補助金、工作時數、污名感受、污名因應、工作滿意度及工作收入滿意度可解釋整體生活品質48.8%之總變異量。其中以污名感受、工作滿意度及工作收入滿意度等變項對整體生活品質最具顯著之解釋力。
結　論　本研究結果可增加健康專業人員，對精神分裂症病人生活品質的瞭解，協助因應污名，增加對工作滿意度，進而改善生活品質。

Background: Quality of life (QOL) is a critical issue in mental health care. The associations between quality of life and schizophrenia patients’ stigma perception and stigma coping behavior are not well understood.
Purpose: This study investigated quality of life in schizophrenia patients.
Methods: We used a cross-sectional, correlational research design; enrolled 119 individuals diagnosed with schizophrenia as participants; and used instruments including a demographics datasheet, perceived stigma scale, stigma coping behavior scale, and the World Health Organization quality of life scale, brief version to collect data. Data were analyzed using SPSS 12.0 for Windows software.
Result: (1) Participants had an average QOL index score of 62.40, indicating moderate quality of life; (2) Long working hours, holding rehabilitation-related employment, and receiving social welfare support correlated with lower QOL; (3) Marital issues had the greatest impact on quality of life, with participants who chose secrecy / concealment reporting generally better QOL; (4) Social welfare support, number of working hours, stigma perception, stigma coping, level of job satisfaction, and level of salary satisfaction together accounted for 48.8% of total QOL variance.
Conclusions: Findings increase our understanding of the influence of socio-demographics, stigma perception, and stigma coping behavior on quality of life in individuals with schizophrenia. Greater community involvement in schizophrenia treatment programs can enhance patient satisfaction with their jobs and lives.