本研究目的是研製壓電超音波振動顯微切割系統，利用壓電致動器質量
輕、體積小、反應快及出力大等優點，來推動切割器末端的刀具，進行高頻運
動，致使刀具更易於刺入組織進行輪廓切割，以切割細胞組織為目的。為了使
切割刀具能精準進行切割，利用影像處理方式，側向校準刀具至載台高度量，
以線性平面步進馬達來改變移動組織被切割之速度，探討切割刀具振動幅值、
頻率、改變切割速度等最佳的工作參數，以有效地減小切割阻力，研究結果顯
示，切割洋蔥表皮細胞邊緣平整，可達降低設備成本，便於日後臨床之使用。

Micro dissection is used to obtain a particular kind of a single cell or
cells from tissue sections such as cell oncogenes, tumor suppressor gens
and enzymes. The purpose of this study is to establish a system based on
piezoelectric ultrasonic micro-tools and motion platform. Using ultra-
sonic vibrations, the micro-cut knife results in easy tissue penetration.
Mechanical vision assists in monitoring the tool positioning and elucidates
the feasibility of cutting. To determine the optimal parameters for dissec-
tion, the vibration amplitude and frequency of the cutting tool were studied.
Resistance force due to micro dissection is reduced thereafter. Finally, a
low cost device for micro dissection in clinical practice is achieved.