敗血性肺栓塞並不常見，且其流行病學因地而異。本研究之目的為探討北台灣敗血性肺栓塞病患的臨床特徵。我們回溯性分析台灣北部某醫學中心自2001年1月1日至2005年12月31日的敗血性肺栓塞病患，分析資料包括病患的臨床表現、放射線學與微生物學檢查、治療以及預後。共有28位病患，平均年齡為44歲，16位男性。最常見的原發感染病灶為三尖瓣心內膜炎(14位)，其次為肝膿瘍(5位)。最常見的致病菌為金黃色葡萄球菌(16位)，其次為克雷伯氏肺炎菌(9位)，19位病患有菌血症。全部病患均接受適當的抗生素治療，4位接受心臟瓣膜置換手術，1位接受筋膜切開術，1位接受肝膿瘍經皮引流。5位病患發生呼吸衰竭，最後3位因為敗血症而死亡。感染性心內膜炎與肝膿瘍是北台灣的肺部敗血性栓塞病患最常見的原發感染源，其致病菌分別是金黃色葡萄球菌與克雷伯氏肺炎菌。

Septic pulmonary embolism (SPE) is an uncommon disease with a diverse epidemiology. The purpose of this study was to investigate the clinical characteristics of SPE in northern Taiwan. A retrospective review of hospitalized patients with SPE from January 1, 2001 to December 31, 2005 was conducted in a medical center in northern Taiwan. The clinical presentations, radiographic findings, microbiological data, treatment and outcomes were analyzed. Twenty-eight patients were included in the final analysis. Their mean age was 44 years, and 16 patients were men. The most common septic source was infective endocarditis of the tricuspid valve (n=14), followed by liver abscess (n=5). Staphylococcus aureus was the causative microorganism in 16 patients, followed by Klebsiella pneumoniae in 9 patients. Bacteremia occurred in 19 patients. All patients were treated with appropriate antibiotics and 4 had a valve replacement for infective endocarditis, 1 had a fasciotomy for necrotizing fasciitis, and 1 had percutaneous drainage of a liver abscess. Respiratory failure developed in 5 patients and 3 patients died. Tricuspid valve endocarditis and liver abscess were the main contributing risk factors in patients with SPE in northern Taiwan, while Staphylococcus aureus and Klebsiella pneumoniae were the causative pathogens in these 2 conditions, respectively.