篇名 | Diagnostic Performance of 64- versus 256-Slice Computed Tomography Coronary Angiography Compared with Conventional Coronary Angiography in Patients with Suspected Coronary Artery Disease |
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卷期 | 29:2 |
作者 | Su-Kiat Chua 、 Huei-Fong Hung 、 Jun-Jack Cheng 、 Min-Tsung Tseng 、 Wai-Yip Law 、 Chu-Jen Kuo 、 Chiung-Zuan Chiu 、 Che-Ming Chang 、 Shih-Huang Lee 、 Huey-Ming Lo 、 Sheng-Chang Lin 、 Jer-Young Liou 、 Kou-Gi Shyu |
頁次 | 151-159 |
關鍵字 | Computed tomography coronary angiography 、 Conventional coronary angiography 、 Diagnostic performance 、 64-slice helical CTCA 、 256-slice helical CTCA 、 MEDLINE 、 SCI 、 Scopus |
出刊日期 | 201303 |
Purpose: The newer 256-slice computed tomography coronary angiography (CTCA) has the capability of improving diagnostic performance in the detection of obstructive coronary artery disease (CAD) compared to 64-slice CTCA. The aim of this study was to compare the diagnostic performance of 64- versus 256-slice CTCA in two similar populations.
Methods: Our study included 120 consecutive patients who were referred for CTCA and subsequently underwent conventional coronary angiography (CCA). Sixty patients were studied by 64-slice CTCA, with the other 60 by 256-slice CTCA. We compared the technical characteristics and diagnostic performance of 64- and 256-slice CTCA for the detection of 50% stenosis of the coronary arteries on CCA.
Results: The 256-slice CTCA had a shorter scanning time (4.4 0.6 sec vs. 5.0 ± 0.7 sec, p < 0.001) compared to 64-slice CTCA. The diagnostic accuracy rates of 256-slice CTCA based on patient analysis (97% vs. 83%, p < 0.05), vessel analysis (95% vs. 85%, p < 0.05), and segment analysis (94% vs. 88%, p < 0.05) were significantly superior to those of 64-slice CTCA. The diagnostic accuracy rates of 64- and 256-slice CTCA were affected by the presence of stent (65% vs. 75%, respectively, p > 0.05) and severe calcifications (75% vs. 82%, respectively, p > 0.05).
Conclusions: In two similar populations, 256-slice CTCA displayed superior diagnostic performance than 64-slice CTCA. However, the performance of 256-slide CTCA is affected in those segments that are severely calcified and/or stented.