隨著環保意識抬頭，人們開始省思如何減少對大自然的危害，在化學界亦開啟了綠色化學（green chemistry)的探討，其目的是要在生產的過程中，能充分利用原科及能源、減少有害物質的釋放以及使反 應效率能夠達到最高。其中流動化學（flow chemistry)即是因應此觀念而產生的一項新技術，雖然此技術在石油化工領域的使用已相當成熟，然而應用在實驗室的反應研究，則僅是近十年才開始發展，主要是希 望能藉此技術提高質能轉換效率、減少溶劑的使用、降低汙染物的生成以及達到全天候自動化工作的目標。近幾年應用於藥物和天然物合成的商品化儀器已被陸續開發出來，克服了許多利用傳統批次式反應器(batch reactor)進行反應時所產生的問題及限制，本文將介紹流動化學的原理、優勢和成功應用的實例。

The increasing environmental awareness leads to a rethinking of ways on how to reduce the harm done to nature. This perception has gradually been brought into the field of chemistry, launching the study of Green Chemistry. Green Chemistry aims to reduce the release of harmful substances and allow reactions to achieve maximum efficiency in the production process by fully utilizing raw materials and energy. To meet these challenges, flow chemistry tools have been developed. Originally used in the petrochemical field but applied in the laboratory only nearly a decade ago, flow chemistry can effectively improve heat/mass transfer opportunities, decrease the solvent usage, lessen waste generation, and make a working regime a possibility. This technique has been applied in drug development and natural product synthesis in nowadays, overcoming many problems caused by conventional batch reactors. Here, we introduce the principles and advantages of flow chemistry and some successful examples on the applications.