散發型庫賈氏病為一罕見的神經性退化性疾病，常見的臨床症狀有進行性失智，步態不穩，肌躍症等。本文報導一位七十二歲的女性，因血糖過高來住院，後來因意識漸漸變差，合併有全身痙孿的現象，才得知罹患此罕見的疾病。為此，我們還採取了一些特別的感染管制措施。在此我們回顧一些文獻，並提出關於此病的發生率、診斷，感染性、器械消毒及感染管制的討論，以提醒臨床醫師在診斷及後續處理上該注意的地方。

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disease. Its clinical symptoms includes rapidly progressive dementia, gait disturbance, and myoclonous etc. We report a 72-year-old woman admitting due to hyperglycemia. Later, evalation of progressive loss of consciousness and deterioration of mentality with myoclonus and generalized convulsion led to the discovery of such a rare disease. We reviewed the literature and discussed the incidence, diagnosis, infectivity, decontamination and infection control of sporadic Creutzfeldt-Jakob disease (CJD). The clinician should pay attention to it and know how to deal with after it was diagnosed.