母乳是新生兒最好的食物，不論在營養成長、免疫調節功能方面，皆優於所有的人工配方製品，又兼有提升母子情感的好處，故母乳是出生後新生兒的最佳選擇。然而有些母親因妊娠前或妊娠時有高血壓，致使哺乳時仍需高血壓藥物的治療，考慮到對新生兒的影響，通常需轉換高血壓藥物。本文整理近年來的研究報告，主要透過高血壓藥物於乳汁中的分泌情形，探討藥物對哺乳期的影響，以及可能對新生兒的副作用，希望藉此選擇出對母親及新生兒最適合的降血壓藥物。在眾多降血壓藥物中，因利尿劑會抑制泌乳的特性，應避免哺乳期使用。就目前的資料來看，methyldopa、乙型阻抗劑有高血漿蛋白結合度（如propranolol）、captopril、enalapril及部分鈣離子阻抗劑似乎是哺乳期有高血壓母親的安全治療法。另外，服藥後3至4小時再哺乳及緩慢增加藥量更可使藥物對新生兒的影響減至最小。

Approximately 14% of women 20-54 years of age have hypertension. Some of these women need antihypertensive treatment postpartum, and wish to breastfeed. Many drugs taken by the mother eventually appear in human milk. The drug level in milk depends on the physiochemical properties of the drug, the degree of plasma protein binding, acid-base characteristics, lipid solubility and the maternal serum concentration. Both the clinician and the mother have to weigh the risk to benefit ratio when maternal medication is prescribed. This article discusses the antihypertensive medication with regard to lactation by the maternal milk to plasma (M/P) ratios and indicates the choice of agents for the mother and infants. It seems reasonable to avoid diuretics, because of their potential to suppress lactation. By the available data to date, Methyldopa, beta blocker with high plasma protein binding (ex propranolol), captopril, enalapril, and some calcium channel blockers are safe treatments of hypertension in a nursing mother, especially with slowly increasing dose and feeding 3-4 hours after taking antihypertensive medicine.