背景：過去的研究對於居住在機構的慢性精神分裂症住民，活動設計的取向多以改善人際互動、情緒或生活品質為主，鮮少是以改善認知功能或淡漠感受為目標。
目的：探討身心機能活化方案介入後，機構的慢性精神分裂症住民於認知功能、淡漠感受和憂鬱情緒的改善成效。
方法：本研究為類實驗性設計，以立意取樣方式，選取北市二所慢性機構中罹患慢性精神分裂症的住民(N = 77)，實驗組(n = 43)參與「身心機能活化方案」，持續三個月，每次90分鐘(一次／週)；對照組(n = 34)則維持一般日常活動。方案介入結束時，樣本完成率為62.3%(實驗組為34位與對照組14位)。研究資料使用SPSS 17.0 Window套裝軟體進行無母數統計相關分析。
結果：方案介入後實驗組認知功能的定向感(χ2 = 8.78, p = .032)與建構力(χ2 = 10.13, p = .016)、憂鬱情緒(χ2 =13.71, p < .001)皆達統計顯著改善。與對照組相比較時，研究對象在認知功能(Z = 2.67, p = .010)及憂鬱情緒(Z = -4.10, p = .010)，亦有統計顯著差異。
結論：身心機能活化方案之介入，可有改善解慢性精神分裂症患者的認知功能與憂鬱情緒，此方案可做為慢性精神分裂症患者改善症狀和避免功能退化的活動參考，對於未來研究，建議延長追蹤時間以利進一步的探討。

Background: Previous studies of institutionalized chronic schizophrenia patients have developed intervention activities designed to improve social interaction, depressive mood, and quality of life. Few interventions have
been designed to improve the cognitive functions and apathy in this patient population.
Objectives: The purpose of this study was to explore the effectiveness of a physical and mental functional activation program (PMFAP) in improving the apathy, depressive mood, and cognitive functions of institutionalized
chronic schizophrenia patients.
Methods: This quasi‐experimental study used purposive sampling to recruit chronic schizophrenia patients (N =77) at two institutions in Taipei, northern Taiwan. The PMFAP was provided to 43 patients in the experimental
group for 3 months (90 minutes per week). The 34 patients in the control group continued their regular daily activities. The completion rate for participants in this study was 62.3% (experimental group: 34; control
group: 14). The SPSS 17.0 software package for Windows was used to conduct non‐parametric statistical analyses.
Results: Residents with chronic schizophrenia in the experimental group earned statistically significant improvements in terms of the orientation (χ2 = 8.78, p = .032) and the constructive ability (χ2 = 10.13, p = .016) dimensions of cognitive function as well as depressive mood (χ2 = 13.71, p < .001). A posttest comparison found significant differences between the two groups in terms of cognitive function (Z = 2.67, p = .010) and
depressive mood (Z = ‐4.10, p = .010).
Conclusion: The results of this study indicate that the PMFAP intervention program improves the cognitive functions and depressive mood of institutionalized chronic schizophrenia patients. Therefore, we suggest
implementing this program with patients with chronic schizophrenia to both improve symptoms and delay degeneration. Future studies should extend the follow‐up time to assess the efficacy of the intervention over longer time periods.