安非它命濫用是時下常見之問題，特別見於年輕人。安非它命及其衍生物所造成之心臟毒性包括心肌梗塞/壞死，心肌病變，心臟衰竭, 心律不整，及心因性猝死.此篇報告為一極為罕見且以往其它文獻未曾報告過之病例。一 34 歲男性於安非它命濫用後同時發生陣發性心室上頻脈 (paroxysmal supraventricular tachycardia) 及急性心肌梗塞 (acute myocardial infarction)。陣發性心室上頻脈於稍後未經治療後停止，此病人隨後接受心臟電氣生理檢查及心律不整燒灼術。而急性心肌梗塞以心肌酵素上升，心電圖ST 節段下降，及明顯血栓見於左前降支至肺動脈之廔管 (fistula) 而診斷。此篇報告主要討論安非它命濫用後發生陣發性心室上頻脈及急性心肌梗塞的不同原因及機制。

Amphetamines are popular drugs of abuse, particular among young people. Cardiotoxicity after the abuse of amphetamines and their synthetic derivatives, including acute myocardial infarction/necrosis, cardiomyopathy, congestive heart failure, arrhythmia, and sudden cardiac death, has been documented but is rare. Herein, we provide details on an extremely rare case which has not previously been reported. A 34-year-old man developed concurrent paroxysmal supraventricular tachycardia (PSVT) and acute myocardial infarction (AMI) after the use of amphetamines. The supraventricular tachycardia spontaneously terminated and AMI was diagnosed by elevated cardiac enzymes, diffuse ST depression on an electrocardiogram, and a thrombus noted in a fistula which ran from the left anterior descending artery to the pulmonary artery. Radiofrequency catheter ablation was used to treat the PSVT in this patient. In the present case report, we discuss the different causes and mechanisms of PSVT and AMI after amphetamine abuse.