目的：國內文獻目前尚無有關混合性聽障患者的生活品質報告，本研究目的為調查罹患混合性聽力障礙病人的生活品質狀況並比較其與台灣成年人整體健康的差異性。材料與方法：本研究以前瞻性、連續性方法蒐集34 名來自醫學中心耳鼻喉科成年混合性聽障患者，除收集臨床資料外並給與病人一份中文版「SF-36 整體健康調查問卷」，SF-36 整體健康狀況8 個次項與聽力資料的關係以Spearman 相關係數呈現，並以複迴歸分析探討相關之影響因子。結果：我們發現混合性聽障患者在「SF-36 整體健康調查問卷」的8 個次項中，皆顯著差於健康成年族群(p<0.05)，而聽力損失時間長短與生理角色功能(RP)、一般健康狀況(GH)、情緒角色功能(RE) 呈現顯著的正相關。結論：混合性聽障患者在日常生活品質的表現上普遍較正常人差，其中以影響病患之社交功能最嚴重，但當聽力損失時間越長，聽力障礙所造成的衝擊也就越小。此提供台灣混合性聽力障礙病人生活品質狀況之參考。

The quality of life (QoL) status in patients with mixed-type hearingimpairment has not been reported domestically. The objectives of this study were to investigatethe QoL of patients with mixed-type hearing impairment and to compare their generic healthstatus with that of a normative Taiwanese adult population. Thisstudy was conducted in a prospective manner by interviewing 34 cases in a local medical center.Clinical data were collected, and the SF-36 (Short Form-36) questionnaire was administered. Thegeneral health status (SF-36) and clinical hearing datawere correlated using Spearman correlationcoefficients. A multiple regression model was used for risk analyses. The general healthstatus of patients with mixed-type hearing impairment was significantly inferior to that of thepopulation norm, as can be seen from the decrements in all 8 dimensions of the SF-36 subscales (p< 0.05) . The period of hearing loss was significantly positively correlated with role functioning -physical ( = 0.602, p = 0.006) , general health ( = 0.574, p = 0.016) , and role functioning - emotional( = 0.517, p = 0.019) . The QoL of patients with mixed-type hearing loss is muchworse than that of the normative population,with especially serious impacts resulting in impairedsocial functioning. Following the time of hearing impairment, the impact of hearing losswas muchlower. This study is an initial report on the QoL in patients with mix-type hearing problems.