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輔仁醫學期刊

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篇名 Non-Enteropathic Hemolytic-Uremic Syndrome after Herb Intake--A Case Report
卷期 5:1
並列篇名 服用草藥後發生溶血性尿毒症候群--一病例報告
作者 陳怡安馮祥華曾嶔元楊垂勳
頁次 43-52
關鍵字 溶血性尿毒症栓塞性微血管病變腎衰竭Hemolytic-uremic syndromeThrombotic microangiopathyRenal failureHerbs
出刊日期 200703

中文摘要

溶血性尿毒症是造成急性腎衰竭一個重要的原因,而且可能會導致腎臟功能永久的傷害。我們報導一位45 歲的婦女,在短暫服用不知名的草藥後,臨床上產生了典型的溶血性尿毒症的情況,在腎臟切片上出現栓塞性微血管病變,吻合此疾病的診斷。病人總共接受了8 次的血漿置換術,其臨床表現、以及血液檢查數據才逐漸穩定。但是很不幸的,病人的腎臟功能仍然沒有恢復。至今,仍需仰賴血液透析的治療。有關溶血性尿毒症的臨床表現、發病原因、及病理變化在此也一併討論。

英文摘要

Hemolytic uremic syndrome (HUS) is an important cause of acute renal failure, and may beirreversible. We describe a 45-year-old woman who developed non-enteropathic HUS soon aftertaking herbal medicine of unknown composition for a few days. A renal biopsy showed glomerularsclerosis and collapse secondary to the glomerular and vascular lesions of thromboticmicroangiopathy. Her clinical condition was stabilized after 8 exchanges of plasmapheresis.However, renal failure persisted, and the patient still depends on long-term dialysis. The clinicalmanifestations, etiologies, and pathologic findings of HUS are discussed.

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