篇名 | Non-Enteropathic Hemolytic-Uremic Syndrome after Herb Intake--A Case Report |
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卷期 | 5:1 |
並列篇名 | 服用草藥後發生溶血性尿毒症候群--一病例報告 |
作者 | 陳怡安 、 馮祥華 、 曾嶔元 、 楊垂勳 |
頁次 | 43-52 |
關鍵字 | 溶血性尿毒症 、 栓塞性微血管病變 、 腎衰竭 、 Hemolytic-uremic syndrome 、 Thrombotic microangiopathy 、 Renal failure 、 Herbs |
出刊日期 | 200703 |
溶血性尿毒症是造成急性腎衰竭一個重要的原因,而且可能會導致腎臟功能永久的傷害。我們報導一位45 歲的婦女,在短暫服用不知名的草藥後,臨床上產生了典型的溶血性尿毒症的情況,在腎臟切片上出現栓塞性微血管病變,吻合此疾病的診斷。病人總共接受了8 次的血漿置換術,其臨床表現、以及血液檢查數據才逐漸穩定。但是很不幸的,病人的腎臟功能仍然沒有恢復。至今,仍需仰賴血液透析的治療。有關溶血性尿毒症的臨床表現、發病原因、及病理變化在此也一併討論。
Hemolytic uremic syndrome (HUS) is an important cause of acute renal failure, and may beirreversible. We describe a 45-year-old woman who developed non-enteropathic HUS soon aftertaking herbal medicine of unknown composition for a few days. A renal biopsy showed glomerularsclerosis and collapse secondary to the glomerular and vascular lesions of thromboticmicroangiopathy. Her clinical condition was stabilized after 8 exchanges of plasmapheresis.However, renal failure persisted, and the patient still depends on long-term dialysis. The clinicalmanifestations, etiologies, and pathologic findings of HUS are discussed.