使用經靜脈注射含嗎啡(morphine) 之病患自控式止痛(patient-controlled analgesia,PCA) 裝置，有逐年增加的趨勢。本報告為一名50 歲的女性病患，因長期打鼾及阻塞性睡眠呼吸中止症(obstructive sleep apnea syndrome) 於2003 年7 月在本院接受懸雍垂顎咽成型術(uvulopalatopharyngoplasty) 後，病人要求麻醉科醫師裝置經靜脈注射含嗎啡之病患自控式止痛裝置。病人於返回病房一小時後，發生急性呼吸抑制；經緊急復甦術後病人回復自主呼吸，於門診追蹤至今6 個月無任何後遺症。本報告提醒在阻塞性睡眠呼吸中止症術後，即使嗎啡的劑量在安全範圍內，仍能引發急性呼吸抑制(acuterespiratory depression)，並討論其預防方法。

Patient-controlled intravenous delivery of morphine for postoperative pain management isconstantly increasing. However, side effects such as constipation, nausea, vomiting, urinaryretention, sedation, postural hypotension, respiratory depression, and addiction are occasionallyseen.We report on a 50-year-old woman who received uvulopalatopharyngoplasty (UPPP) due toobstructive sleep apnea syndrome (OSAS) in July 2003. She asked for patient-controlled analgesiain the recovery room after waking up from general anesthesia. Acute respiratory depressionoccurred 1 hour after returning to theward. Spontaneous respiration was regained after immediateresuscitation, and no complications were noticed over the 6-month follow-up period. PCA-relatedacute respiratory depression after UPPP in OSAS patients may occur even if the dosage ofmorphine used is within the safe range.