Lemierre's syndrome是急性咽喉炎合併化膿性內頸靜脈血栓靜脈炎，通常與梭狀桿菌菌血症(Fusobacterium necrophorum bacteremia)有關，而且常發生轉移性膿瘍，尤其是肺膿瘍最常見。其初期臨床表現酷似病毒性咽喉炎，所以在此提出二病例報告以提醒臨床醫師及早發現給予適當治療以扭轉此可能致命之疾病。

Lemierre's syndrome-the forgotten disease, is a suppurative thrombophlebitis of the internal jugular vein caused by Fusobacterium necrophorum bacteremia, in the antecedent presence of oropharyngeal infection mimicking viral pharyngitis and it can be complicated by metastatic abscesses formation, most commonly in the lungs. Two cases of Lemierre's syndrome are presented to remind physicians about the unique clinical pictures of the forgotten disease in Taiwan. Early recognition and appropriate antibiotic treatment will cure this possibly life-threatening disease.