生於薦椎前空間的表皮囊腫是一種少見的先天病灶。表皮囊腫內有惡性腫瘤細胞更是極為 罕見。經過文獻的搜尋，相同的案例目前只有一篇英文的影像報告與四篇日文的個案報告曾被 發表。在此我們報告了一名六十二歲的女性，經過檢查後被診斷於薦椎前空間有一囊腫。這名 患者接受了 Kraske 氏手術以移除囊腫腫塊。病理檢查發現內含鱗狀上皮細胞癌細胞。因為腫塊 在術中破裂了，患者接著接受了術後的輔助放射線治療，劑量是五十戈雷／二十五分次。經過 了一年的追蹤，患者並沒有腫瘤復發的跡象。

　　Epidermoid cyst of the presacral space is a rare congenital lesion. Cases of malignance arising from the lesion are extremely rare. After searching the literature, there are only 1 image report in English literature (PubMed) and 4 cases reports in Japanese literature of the disease. Here we report a 62-year-old female who was diagnosed with presacral cyst before surgery. Wide excision of the cystic tumor by Kraske's operation was performed. The pathology showed squamous cell carcinoma. Because of tumor rapture during operation, adjuvant radiotherapy 50 Gray/ 25 fractions was performed. After 1 year follow up, there is no evidence of disease.