副神經節細胞瘤，被稱為腎上腺外的嗜鉻細胞瘤，是罕見的神經內分泌腫瘤。它的症狀和表現不具特異性，有些腫瘤會分泌過多的兒茶酚胺而引發症狀。它大部分只發生在單獨一處；然而當它發生在很多地方時，通常被認為是一個遺傳疾病的綜合症狀的一部分，例如多發性內分泌腫瘤。它最重要的診斷要素取決於仔細的檢查出此腫瘤混合的三個細胞類型。此腫瘤大多都是良性的表現，雖然少部分(15-35%的病例)會有淋巴結轉移，就會被診斷為惡性。手術依然是所有副神經節瘤的主要治療方式。在此我們報告一個長在十二指腸的副神經節細胞瘤病例。

Paragangliomas, known as extra-adrenal pheochromocytomas, are rare neuroendocrine tumors. The symptoms and signs are nonspecific and related to excess secretion of catecholamine. Paragangliomas occur as single tumors. However, when they occur in multiple sites they are usually found as a part of a heritable syndrome such as multiple endocrine neoplasia types II-A and II-B and succinate dehydrogenase (SDH) related mutations. Recognition and diagnosis depends on careful examination for the three cell types (epithelioid/ neuroendocrine cells, spindled cells, and ganglion cells) that characterize the tumor. Its behavior is usually benign, although some have lymph node metastasis and are diagnosed as malignant (15-35% of the cases). Surgery remains the mainstay of treatment for all paragangliomas. Herein, we report a case of gangliocytic paraganglioma located in the duodenum that was completely excised. (J Intern Med Taiwan 2014; 25: 122-126)