背 景：高壓力職場環境使護理人員成為高盛行率之職場疲勞族群，不僅影響護理人員之身、心健康，間接影響病患照護品質。
目 的：本研究目的為調查護理人員之工作壓力與職場疲勞概況、探討個人與工作屬性及工作壓力與職場疲勞之相關性、並分析影響職場疲勞重要預測因子。
方 法：本研究採橫斷相關性研究設計，於臺灣北部某醫學中心進行收案，採方便取樣，共收集117位護理人員，以結構式問卷進行資料收集，問卷包含：基本資料表及工作特質與職場疲勞量表，以SPSS 20.0版進行資料統計分析。
結 果：本研究對象整體職場疲勞平均得分為44.90，其中以「個人疲勞」平均分數最高為48.80、其次為「工作疲勞」47.74分；其中有無子女(t = 2.25, p < .05)與有無宗教信仰(t = 2.07, p < .05)與職場疲勞有顯著差異性，與自覺工作壓力(r = .44, p < .01)與生活壓力(r = .33, p < .01)、工作負荷(r = .36, p < .01)與職場疲勞呈正相關，缺乏職場正義者(r = -.21, p < .05)與職場疲勞呈負相關；其中有無子女、宗教信仰、自覺工作壓力及工作負荷為顯著重要預測因子，共可解釋34%職場疲勞變異量。
結論/臨床應用：行政管理人員應針對個人疲勞與工作疲勞較高的護理人員，主動提供資源協助其調適工作壓力，並應用本研究發現之護理人員職場疲勞的影響因素，擬訂改善策略，有效降低其工作壓力，進而減輕人員的職場疲勞。

Background: High-pressure workplace environments lead to a high prevalence of occupational burnout among nurses. This affects the physical and mental health of nurses and the quality of patient care.
Purpose: This study investigates the current state of job stress and burnout and the relation between these two variables in order to explore the significant predictors of occupational burnout.
Methods: A cross‐sectional survey was conducted at a medical center in northern Taiwan using a convenience sample of 117 nurses. Data were collected in a structured questionnaire that included: a demographic inventory, a job content questionnaire, and an occupational burnout inventory. Data were analyzed using SPSS for Windows 20.0 software.
Results: The average score for occupational burnout was 44.90, with the highest mean score in the aspect of personal fatigue (M = 48.80), followed by work-related fatigue (M = 47.74). This research found occupational burnout to be significantly associated with the presence of children (t = 2.25, p < .05), religious belief (t = 2.07, p < .05), perceived work and life stress (r = .44; .33, p < .01), workload (r = .36, p < .01), and workplace justice (r = -.21, p < .05). The presence of children, religious belief, perceived work stress, and workload were significant predictors, with these 4 predictors explaining 34% of the total variance in occupational burnout.
Conclusions / Implications for Practice: Supervisors should provide resources to help nurses handle job stress. The findings of this study may be applied to develop a more effective interventional approach to decrease the job stress of nurses and to ameliorate their perceived burnout.