目的：探討社區牙周指數(community periodontal index ； CPI)、牙菌斑指數(plaque index ； PI)、缺牙數 目、血液中脂聯素(adiponectin)和高敏感度C-反應蛋白 (high sensitive C-reactive protein ; hs-CRP)濃度與心血管 疾病的相關性。 方法：從大同醫院健康檢查單位收集對照組63人 和心臟內科門診收集心血管疾病患者101人，在簽署同 意書後以問卷收集基本資料和潛在干擾因子的資料， 並抽血5-8ml進行生化檢測，以兩位經一致化和標準化 訓練的牙醫師收集社區牙周指數和牙菌班指數來評估口 腔健康狀態，最後以SPSS 19.0統計軟體分析其相關性。 結果：本研究調查對象平均年齡為57.6 ±11.8歲。 有抽菸習慣、已婚、年齡>57歲、HbAlc>7%、CPI> 3、缺牙顆數 >4、total cholesterol >200 mg/dL、fasting glucose> 116 mg/dL、adiponectin < 24 )ig/mL、PI>2、 hs-CRP>5 mg/L、TG>160 mg/dL和LDL> 130 mg/dL

Objectives: Our aims were to determine the association between community periodontal index (CPI), plaque index (PI), number of tooth loss，plasma levels of adiponectin and high sensitive C-reactive protein (hs-CRP)，and cardiovascular disease (CVD). Methods: Sixty and three controls were recruited from hospital visiting for health examination, and 101 CVD patients were recruited from the Division of Cardiology, Municipal Ta-Tung Hospital, Kaohsiung, Taiwan. A standardized questionnaire was applied to collect demographic and potential confounding variables after the inform consent was obtained. A total of 5-8 ml of peripheral blood was collected for the biochemistry tests. The CPI and PI values were assessed by two well-trained dentists. After the data merged，statistical methods were applied to determine the association by SPSS19.0 • Results: The mean age of all participants was 57.6 土 11.8 years old. The frequency distributions of smokers, status of married, age >57, HbAlc>%, CPI>3? number of tooth lost>4? total cholesterol >200 mg/dL, fasting glucose >116mg/dL, adiponectin < 24 )ig/mL，PI >2, hs-CRP >