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物理治療

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篇名 癲癇症患者的運動訓練:機制、療效、及介入之文獻回顧
卷期 40:1
並列篇名 Exercise Training in Patients with Epilepsy: Exercise Mechanisms, Effects, and A Literature Review on Interventions
作者 李鑌張光華陳弘欣張婷方陳曉宜
頁次 001-010
關鍵字 癲癇症運動訓練身體活動EpilepsyExercise TrainingPhysical ActivityTSCI
出刊日期 201503
DOI 10.6215/FJPT.PTS1406188293

中文摘要

癲癇症指的是因基因或腦部疾病造成不停再發的腦細胞異常過度放電,癲癇發作的種類分為局部性和全身性。癲癇症除了癲癇的發作造成患者的困擾,也常伴隨沮喪、焦慮等心理問題,及較高的死亡率。目前癲癇症之第一線醫療介入仍是藥物治療,但為了避免過度使用藥物,患者們通常會接受其他輔助治療,而運動治療則是其中之一》運動訓練不僅可以藉由調節大腦神經元及改善腦部能量代謝1來降低癲癇及與其相關共病症之發生,並可減少心血管疾病之相關危險因子及抗癲癇藥物引起之副作用。文獻回顧結果顯示,持續服藥的癲癇症患者,執行輕度到中度之運動可以減少癲癇發作的頻率 > 且對患者之生活品質有正向影響;而執行最大運動測試時,癲癇症患者不會有癲癇發作的情形,且過程中其大腦皮質癲癇樣放電波有減少的傾向。運動訓練引起癲癇發作的機率極低,不管癲癇症患者其癲癇發作之種類及頻率,在適當的環境且有規律服用抗癲癇藥物的狀況下,執行運動訓練對這些病患是有助益的。(物理治療2015;40(1):1-10)

英文摘要

Epilepsy is characterized by recurrent electrical hypersynchronization of neuronal network in the cerebral cortex due to a genetically determined or required brain disorder. There are two broad categories of seizures- partial and generalized types. Concerns of these patients include the recurrence and complications, such as depression, anxiety and the high mortality rates. The primary management of epilepsy is through medication, especially antiepileptic drugs therapy. In order to prevent overuse of medicine, non-pharmacological therapies, such as exercise training, are suggested. Through modulating neuronal vulnerability and brain metabolism, exercise training can minimize comorbidities associated with epilepsy. Besides, it can modify the occurrence of risk factors related to cardiovascular disease and the side effects of medication. According to the literature, patients with medication control show a decrease in seizure attacks, and the number of epileptiform discharges decreases during strenous exercise. Moderate intensity exercise reduces the incidence of seizure attacks and has a positive effect on patients’ quality of life. Seizures induced or exacerbated by exercise are relatively uncommon in patients with epilepsy. With appropriate temperature and humidity controls, exercise training is suggested for patients with regular medication control. Mechanisms of exercise benefits, exercise protocols, and literature evidence are provided in this review. (FJPT 2015;40(1):1-10)

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