傳統上，骨質疏鬆症和心血管疾病被認為是單獨的慢性疾病。現在越來越多的證據支持骨質疏鬆症與高血壓、血脂代謝異常、動脈粥樣硬化、血管鈣化和充血性心臟衰竭之間的直接關聯。近年來病理生理關係在骨質疏鬆症與心血管病的常見危險因素方面取得了重大進展。而這些共同的病理生理機制能如能進一步地理解，可能有助於未來對骨代謝和心血管疾病的治療方法。

Osteoporosis and cardiovascular disease (CVD) were thought to be separate chronic diseases, traditionally. More and more new evidence current supports a direct association between osteoporosis and hypertension, atherosclerosis, dyslipidemia, congestive heart failure, and vascular calcification. Several developments have been made in recent years in clarify the pathophysiological relationship and common risk factors between CVD and osteoporosis. An upgraded understanding of the pathophysiological mechanisms corporate to these conditions may contribute to future development of therapies that can benefit on both bone metabolism and CVD. (J Intern Med Taiwan 2015; 26: 77-87)