The emergence of motion sensing technology has brought digital revolution and affected group and human– computer interaction. Traditionally, reading guidance activities were demonstrated as either the paper-based or keyboard and mouse-based reading guidance scenario which not only could limit the actions and interactions between the teacher and students but also reduce the interest and attention of students. Therefore, the purpose of this study is to integrate the Kinect device in proposing that a motion sensing technology interaction assisted the reading guidance system to facilitate 30 elementary school students in reading guidance learning activities. Students’ interest, attention, and acceptance were investigated. Moreover, this study investigated the teachers’ information literacy and acceptance of applying the motion sensing technology in teaching. The findings reveal that the positive impact of motion sensing technology interaction on teaching activities leads students to enhance interest and attention while engaging in learning activities. Additionally, these teachers believed that integrating motion sensing technology into teaching and learning activities could improve student participation and teacher–student interactions. The results of the study are discussed and implications are provided.