This article considers the dynamic multi-layered process of preparing White preservice art teachers to teach to diversity in urban settings within the United States of America. Topics are centered on three major categories: teacher education responsibility, teacher education challenge, and teacher education opportunity. The teacher education responsibility section examines teacher educators’ roles and responsibilities towards empowering preservice teachers to teach from a perspective that draws upon the histories and experiences of students from increasingly diverse cultural backgrounds. The teacher education challenge looks at some of the problems and issues associated with preparing future teachers to develop their teaching skills and acquire attitudes that will enable them to respect cultural differences and hold high expectations for their students. The teacher education opportunity portion considers opportunities presented by challenges.