A short review of the genus Cleisostoma in the flora of Vietnam is presented with 9 sections and 28 species among which 9 are locally endemic. Present data show the territory of Vietnam as the richest center of diversity for the genus. Two monotypic sections (Gastrochilopsis, Pterogyne) and three species (Cleisostoma lecongkietii, C. phitamii, C. tricornutum) are described as new for science, two species (C. subulatum, C. linearilobatum) are reported on the base of voucher specimens as a new record for the flora of Vietnam.