磁振造影(Magnetic Resonance Imaging, MRI)是一種無輻射性及非侵入性的影像檢查方法，在磁振造影檢查中 可使用反轉回復(Inversion Recovery, IR)波序，運用設置不同的反轉延滯時間(inversion delay time, TI)進行掃描，來 抑制掉可能對於影像判讀有影響的訊號，有助於臨床醫生診斷病例，在MRI 臨床上相當重要。本研究中為了深 入了解反轉回復波序的原理及應用，我們配製了不同濃度的硫酸銅(CuSO4)水溶液代表不同的組織，先設定了五 個不同的TI 值使用1.5T 的磁振掃描儀進行預掃描；從所得的影像中分別求取每支試管中訊號的平均值，然後繪 製不同濃度的硫酸銅水溶液的縱向回復(T1)曲線，根據縱向回復曲線與X 軸的交叉點，可得到各個不同濃度試管 的TI 值。最後，我們再次以磁振造影技術的反轉回復波序，驗證使用這些特定的TI 值時確實可使得相對應之試 管的訊號消失。此一研究證實，我們可以使用這個方法正確的量測出掃描當下各個器官組織的TI 值，然後使用 校正之後的TI 值可進一步更有效的抑制對影像判讀有影響的訊號。因此，將使得腫瘤的侵犯程度跟範圍可以更 準確地被顯示出來，而有助於臨床上可以更加有效率的執行手術與治療。

Magnetic Resonance Imaging (MRI) is a no-radiation and non-invasive imaging method, by change the inversion delay time (TI) of inversion recovery (IR) pulse sequence, people can suppress out signals that may affect image interpretation and help accurate diagnosis. Therefore, IR pulse sequence is very important in MRI applications. To deeply understand the principles and applications of it, we firstly prepared various concentrations of copper sulfate (CuSO4) aqueous solution on behalf of different organs. At beginning, we randomly set five different pre-scan TI values on a 1.5 T magnetic resonance scanner and obtained averaging signals from MR images of each tube. Then the longitudinal recovery curves of all tubes were generated from these signals. After that, the exact TI value of each tube was acquired according to the intersection point of its longitudinal recovery curve and X-axis. Finally, we use these newly generated TI values to verify that the signal came from specific tube could be eliminated by corresponding TI value. This study confirmed that we can use this method to measure the correct TI values of various organs and tissues at the moment of scanning. Then, the adjusted TI value can be further suppressed more effectively of signals affecting image interpretation. Thus, the entrenched extent and range of the tumor can be displayed more accurately and will provide more efficient implementation of surgery and clinical treatment.