我們向毒品宣戰至今已逾二十年。據法務部統計資料，近年來毒品濫用問題已獲穩定控制，但再犯率卻仍然很高，顯示毒品問題並未根絕，尤其青少年學生濫用新興毒品問題日趨嚴重，更引起政府與社會各界的重視。在查緝毒品方面，均採取尿液檢測方式對於吸毒者之查緝及鑑驗，但仍存有多項限制。唾液及汗液檢測則是新興及可行方式，考量到樣本採集和檢測之便利性等因素後，則以唾液檢測最具突出的做法。唾液檢測閾值在各國之間有著差異，因為國情、人種及飲食代謝等因素均我國不同，故設計唾液快速篩選檢測試劑，並研究訂定本土濫用藥物唾液檢測的閾值是非常重要的。

We have been in the war on drugs for over twenty years. According to data from the Ministry of Justice, in recent years, drug abuse problem is under control, but the relapse rates are still high. The teenage student of emerging drug abuse problems caught the attentions of government and society. In drug control activities, drug urine tests are used for arresting and identifi cation of drug addicts. However, this test method does show a number of restrictions to limit the test profi ciency. Saliva and sweat detections are both emerging and feasible method drug-testing approaches, after taking sample collection and test sample authentication into consideration; saliva test method is the most prominent approach. Thresholds of saliva test for drugs are nation by nation, and a variety of factors, including conditions, race and diet metabolism also infl uence the thresholds. In order to design the saliva rapid screening test kits, it is important to establish local drug thresholds.