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放射治療與腫瘤學

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篇名 THE ESSENTIAL ROLE OF TOTAL NEURO-AXIS SURVEY IN A MEDULLOBLASTOMA PATIENT WITH POSTOPERATIVE QUADRIPLEGIA: A CASE REPORT
卷期 23:2
並列篇名 詳細神經軸評估於髓母細胞瘤術後四肢癱瘓病人之重要性:一個病例報告
作者 陳良政洪世凱李文星邱文彥沈秉杰蔡維達林怡安謝慧苓林柏豪郭心語林宏益
頁次 137-143
關鍵字 髓母細胞瘤四肢癱瘓放射治療MedulloblastomaQuadriplegiaRadiotherapyTSCI
出刊日期 201606
DOI 10.6316/TRO/201623(2)137

中文摘要

髓母細胞瘤大部分長自顱後窩,約佔 15%-20% 的兒童中樞性神經腫瘤。手術是髓母細胞 瘤的主要治療方式。臨床上,手術後發生四肢癱瘓的情況非常少見。本文報告一位於術後發生 四肢癱瘓的髓母細胞瘤病患,一開始此情況被認為是無法治癒的術後病發症。然而在詳細的影 像判讀後,我們於 T2W 核磁共振影像上看到第 6 節頸椎有部分的訊號增加,無法完全排除腫 瘤浸潤的可能性。在與病人的家屬詳細討論治療的好處及壞處後,病人接受了術後放射治療, 並在治療後臨床症狀得到顯著地改善。此病例提醒我們在合併有腫瘤相關神經學症狀的髓母細 胞瘤病人身上,放射治療扮演了重要的角色。

英文摘要

Medulloblastoma, mainly arising from the posterior cranial fossa, accounts for 15%-20% of pediatric central nerve system (CNS) tumors. Surgical resection is the major treatment modality used to manage medulloblastoma. Clinically, very few patients develop quadriplegia after surgery. We report a case of medulloblastoma patient developing quadriplegia postoperatively which was initially thought to be secondary to surgery but was later found to due to leptomeningeal carcinomatosis of the cervical spine. Postoperative radiotherapy significantly improved the patient’s symptoms. The positive outcome in this patient is a reminder of the pivotal role radiotherapy plays in the management of cancer-related neurologic dysfunction in medulloblastoma patients.

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