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中華職業醫學雜誌

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篇名 Littoral cell angioma of the spleen in a child
卷期 23:4
並列篇名 裏細胞血管瘤
作者 黃婉愉許佳菁周宇光黃崇濱李慕臻
頁次 283-290
關鍵字 definite diagnosisLittoral cell angiomapathologyhospitalsplenectomy裏細胞血管瘤診斷病理醫院脾臟切除TSCI
出刊日期 201610

中文摘要

裏細胞血管瘤(littoral cellangioma)是個罕見的脾臟腫瘤,來源於脾臟內皮竇岸細胞,一 般認為LCA屬於良性腫瘤,但近年來有惡性腫瘤病例被報導,而且有機會合併其他內臟惡 性腫瘤或免疫調節異常疾病,影像學可見多數結節狀低回音特性之病灶,病人在臨床上可 能完全沒有症狀。在脾臟切除術前很難區分出良性還是惡性,藉由病理形態學改變與免疫 組織化學標誌來做確診,建議患者定期接受臨床追蹤。 本文報告一位六歲的男性,因出現左上腹痛及倦怠一個月,至本院門診求診,理學檢 查觸診發現左上腹疼痛感;實驗室檢查亦無明顯異常數值。經安排腹部超音波及腹部電腦 斷層檢查則顯示脾臟腫瘤,進行脾臟切除術後,病理報告結果爲裏細胞血管瘤(littoral cell angioma)

英文摘要

Littoral cell angioma (LCA) is an extremely rare primary splenic tumor that arises from the littoral cells in the splenic red pulp sinuses lining venous sinuses of normal spleen[10]. It is difficult to distinguish of this tumor preoperatively from other benign or malignant splenic entities . [2] The majority of cases radiologically menifested as small multiple nodules [4]. Definite diagnosis can be confirmed at pathology following splenectomy. [10] Various malignancies with autoimmune and congenital disorders are associated in recent published reports although LCA is considered of a benign and incidental lesion.[3][4] Long-term close follow-up of patient with LCA is recommended . In this paper, we represented a six-year-old boy was admitted to our hospital with an one-month history of anorexia, weakness and intermittent left upper abdominal pain . The combination of abdominal ultrasound (USG) and computed tomography (CT) detected one solitary splenic lesion. Splenectomy was implemented. Final diagnosis of this patient was confirmed postoperatively at pathology.

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