The aim of this paper is developing a quantitative model based on gray theory for predicting the trend of tones for culture-innovative fashion colors by using JCC40 matrix color system. Through the time series composed of the summation of the color suggestion ratios nominated by international forecasting facilities such as INTERCOLOR, JAFCA,…etc. for the past few years, the GM(1,1) model has been applied to induce a predicting equation for the trend of the tone of each color. The results show the predicted trends for color tones are rather in consistence to the real ones as expected. Through the help of the predicted trend results in color tones, the efficiency of culture-innovative creation for the designer in culture-innovative industry can be improved.