製備了氧化石墨烯並對其進行功能化改性，包括羧基化改性、氨基化改性，最終得到石墨烯基 季銨鹽。通過紫外-可見光光譜儀和掃描電鏡等測試表徵了氧化石墨烯(GO)、羧基化石墨烯 (GO-COOH)和石墨烯基季銨鹽(GQAS)對革蘭氏陰性大腸桿菌和革蘭氏陽性金黃色葡萄球菌 的抗菌性能。結果顯示石墨烯基季銨鹽對大腸桿菌的抑菌率達到89.3%，對金黃色葡萄球菌的 抑菌率達到94.0%。將石墨烯基季銨鹽分散於聚丙烯腈/N, N-二甲基甲醯胺(DMF)溶液中，通 過浸沒沉澱相轉化法製備了石墨烯基季銨鹽/聚丙烯腈抗菌膜。探討了影響膜的親水性最大的 因素是石墨烯基季銨鹽的品質濃度。隨著其品質濃度的增加，拉伸膜的拉伸強度越來越大，但 當品質濃度為500 pg/mL時強度最大。

Graphene based quaternary ammonium salt (GQAS) has been fabricated through a series of derivative of graphene such as carboxylated graphene oxide(GO-COOH) amino-functionalization graphene oxide (AGO) in the aim of enhancing the antibacterial properties of graphene oxide. The antibacterial activity to Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus).of GO GO-COOH and GQAS were compared and contrasted by UV-Vis spectrometer and scanning electron microscope (SEM). The results indicated that the antibacterial rates of GQAS are 89.3% and 94.0% to E. coli and S. aureus GQAS was dispersed in polyacrylonitrile(PAN)/N, N-dimethyllformamide (DMF). GQAS/PAN membrane was prepared utilizing the method of immersion precipitation phase inversion. The key impact of hydrophilic performance is the mass concentration of GQAS. The tensile strength of the membrane increased with increasing the mass concentration of GQAS, and the mass concentration of 500 ^g/mL is the strongest through the tensile test respectively.