肢端肥大症乃因青春期後患者的生長素和似胰島素生長因子-1 分泌過多，進而導致全身 組織器官不正常的增生或肥大，包括外表改變等多種病理變化的慢性內分泌疾病。主要是因 腦下垂體生長素瘤所致。盛行率約為每百萬人 40-125 例，每年新增約 3-4 例/ 每百萬人。本 共識乃由國內這方面之專家開會數次達成之共識，就其診斷、治療和追蹤提出大致之見解， 供大家做為這個疾病診治上之參考。

Acromegaly is due to overproduction of GH and insulin-like growth factor-1 after puberty, which resulting in abnormal hyperplasia or hypertrophy of generalized organs. These include appearance and other pathological changes. It is a chronic endocrine disorder. The major cause is growth hormone producing tumor of the pituitary gland. The prevalence rate is 40-125/1,000,000. Annual increase of 3-4 cases/1,000,000. This consensus of diagnosis, treatment and follow-up of acromegaly is formed after several meetings of specialists in this field in Taiwan, to provide for the reference of management of this disorder. (J Intern Med Taiwan 2016; 27: 283-294)