庫欣氏症 (Cushing’s syndrome, CS) 是由於患者體內糖皮質素 (glucocorticoid) 過多，從而 導致全身一系列代謝混亂和病理變化的一種疾病。此病可依照患者的糖皮質素來源、對促腎 上腺皮質素 (adrenocorticotropic hormone, ACTH) 的依賴性、以及病灶進行分類；其中庫欣氏 病 (Cushing’s disease, CD) 即為一種常見類型，其定義為腦下垂體腫瘤分泌過多的 ACTH，進 而導致體內糖皮質素的分泌過多。本共識乃由國內這方面之專家開會數次達成之共識，就其 診斷、治療和追蹤提出大致之見解，供大家做為這個疾病診治上之參考。

Cushing’s syndrome is related the excess of glucocorticoid in the body of the patient, resulting in the specific abnormality and pathological changes. This disease may be classified according to the origin of excess of glucocorticoid, and whether it is ACTH dependent. Cushing’s disease is related to the overproduction of glucocorticoid from the stimulation of ACTH of the pituitary tumor. This consensus of diagnosis, treatment and follow-up of Cushing’s disease is formed after several meetings of specialists in this field in Taiwan, to provide for the reference of management of this disorder by the readers. (J Intern Med Taiwan 2016; 27: 295-308)