篇名 | One-Year Outcomes of Acute Decompensated Systolic Heart Failure in Taiwan: Lessons from TSOC-HFrEF Registry |
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卷期 | 33:2 |
作者 | Hung-Yu Chang 、 Chun-Chieh Wang 、 Yen-Wen Wu 、 Pao-Hsien Chu 、 Chih-Cheng Wu 、 Chih-Hsin Hsu 、 Ming-Shien Wen 、 Wen-Chol Voon 、 Wei-Shiang Lin 、 Jin-Long Huang 、 Shyh-Ming Chen 、 Ning-I Yang 、 Heng-Chia Chang 、 Kuan-Cheng Chang 、 Shih-Hsien Sung 、 Kou-Gi Shyu 、 Jiunn-Lee Lin 、 Guang-Yuan Mar 、 Kuei-Chuan Chan 、 Jen-Yuan Kuo 、 Ji-Hung Wang 、 Zhih-Cherng Chen 、 Wei-Kung Tseng 、 Wen-Jin Cherng 、 Wei-Hsian Yin |
頁次 | 127-138 |
關鍵字 | Beta-blocker 、 Heart failure 、 Mortality 、 Renin-angiotensin blockade 、 Taiwan 、 Treatment 、 MEDLINE 、 SCI 、 Scopus |
出刊日期 | 201703 |
DOI | 10.6515/ACS20170202A |
Background: Heart failure (HF) is a global health problem. The Taiwan Society of Cardiology-Heart Failure with reduced Ejection Fraction (TSOC-HFrEF) registry was a multicenter, observational survey of patients admitted with HFrEF in Taiwan. The aim of this study was to report the one-year outcome in this large-cohort of hospitalized patients presenting with acute decompensated HFrEF. Methods: Patients hospitalized for acute HFrEF were recruited in 21 hospitals in Taiwan. A total of 1509 patients were enrolled into the registry by the end of October 2014. Clinical status, readmission rates and dispensed medications were collected and analyzed 1 year after patient index hospitalization. Results: Our study indicated that re-hospitalization rates after HFrEF were 31.9% and 38.5% at 6 and 12 months after index hospitalization, respectively. Of these patients, 9.7% of themwere readmittedmore than once. At 6 and 12 months after hospital discharge, all-cause mortality rates were 9.5% and 15.9%, respectively, and cardiovascular mortality rateswere 6.8% and 10.5%, respectively. Twenty-three patients (1.5%) underwent heart transplantation. During a follow-up period of 1 year, 46.4% of patients were free from mortality, HF re-hospitalization, left ventricular assist device use and heart transplantation. At the conclusion of follow-up, 57.5% of patients were prescribed either with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers; also, 66.3% were prescribed with beta-blockers and 40.8% were prescribed with mineralocorticoid receptor antagonists. Conclusions: The TSOC-HFrEF registry showed evidence of suboptimal practice of guideline-directed medical therapy and high HF re-hospitalization rate in Taiwan. The one-year mortality rate of the TSOC-HFrEF registry remained high. Ultimately, our data indicated a need for further improvement in HF care.