目的：肥胖為重要健康議題，中央型肥胖會增加心血管疾病的風險。本研究藉由分析醫 院員工體檢的資料，歸納出醫療從業人員中央型肥胖的盛行率及其相關健康風險影響，並且 研究腰圍是否為導致心血管疾病風險增加的危險因子，希望藉此喚起醫療院所對職場中央型 肥胖的重視。 方法：本研究為橫斷性研究，以民國104及105年度北部某醫院員工健檢的資料，將研究 對象分為中央型肥胖與非中央型肥胖兩組，進行描述性統計及推論性分析。並以邏輯斯迴歸 分析腰圍是否為十年心血管疾病中高風險(Framingham risk score≧10%)的獨立預測因子。 結果：本研究總樣本數為849人，其中男性339人，女性510人，平均年齡為43.29±8.59 歲。中央型肥胖者有264人，其中男性員工有35.4%為中央型肥胖者，女性員工有28.2%為中央 型肥胖者。在基本人口學及臨床檢驗特性分析，中央型肥胖者相較於非中央型肥胖者，在新 陳代謝相關因子如血壓、身體質量指數、十年心血管疾病風險、丙胺酸轉胺酶、肌酸酐、空 腹血糖、總膽固醇、高密度脂蛋白膽固醇、低密度脂蛋白膽固醇、三酸甘油酯、尿酸，以及 性別等皆達統計上之顯著相關。經由多變項邏輯斯迴歸分析校正心血管疾病相關危險因子 後，仍發現腰圍是十年心血管疾病中高風險的獨立危險因子。 結論：研究結果顯示男性醫療從業人員比一般男性民眾，有較高的中央型肥胖的比率。 中央型肥胖和許多代謝症候群的危險因子相關，且會增加十年心血管疾病的風險。建議盡量 改善生活型態以減少腰圍，並控制血壓、血糖、膽固醇，以降低心血管疾病的發生。

Introduction: Obesity is an important health issue in modern industrial society. A lot of research have found central obesity increases the risk of metabolic and cardiovascular diseases. Despite better awareness of the negative impacts of central obesity compared to the general population, hospital workers do not necessarily make better lifestyle and diet modification. In this research, we analyze the health check-up data and infer the prevalence of central obesity and related health risk in hospital workers. We also looked into the risk factors which is related to intermediate or high Framingham risk score, hoping by increasing the attention in workplace central obesity, we can improve lifestyle and decrease health-related risk. Method: This cross-sectional study includes data of health-care workers’ annual check-up from a hospital in northern Taiwan in 2015 and 2016. We used Chi-square test to gender and Student t test to other demographic and clinical laboratory data. We used logistic regression to analyze the possible variables which are related to equal or more than 10% of Framingham risk score. Results: The total sample size is 849, with 339 males and 510 females. The average age is 43.29±8.59 years old. There are 264 people with central obesity. Analyzing it by gender, in male hospital workers, 35.4% has central obesity. In female hospital workers, 28.2% has central obesity. Regarding demographic and clinic lab characteristics, we found people with central obesity have statistically significant metabolic related risk factors, such as higher blood pressure, body mass index, Framingham risk score, ALT, Creatinine, fasting plasma glucose, total cholesterol, low density lipoprotein, triglyceride, uric acid, and lower high density lipoprotein. By multivariate logistic regression, after adjusting the risk factors of cardiovascular disease, we still found waist circumference an independent riskfactor in Framingham risk score intermediate and high risk group. Conclusion: This study showed male hospital workers have higher rate of central obesity compared to male general population. Central obesity is related to many factors of metabolic syndrome, and it increases the ten-year cardiovascular disease risk. To lower the risk of cardiovascular disease, we suggest lifestyle modification by light food, regular exercise, and good control of blood pressure, blood sugar, and cholesterol.