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藥物食品分析 MEDLINESCIEScopus
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| 篇名 | Determination of Isosorbide Nitrate and Its Analogues in Pharmaceuticals by High-Performance Liquid Chromatography |
|---|---|
| 卷期 | 2:4 |
| 作者 | FANG-YING TSAI 、 CHIN-JUNG CHEN 、 CHUN-SHENG CHIEN |
| 頁次 | 271-280 |
| 關鍵字 | MEDLINE 、 Scopus 、 SCIE |
| 出刊日期 | 199412 |
中文摘要
英文摘要
A reversed-phase column liquid chromatographic method was developed for analysis of isosor, bide dinitrate (ISDN), isosorbide 5-mononitrate (IS5MN) and isosorbide 2-mononitrate (IS2MN) and its pharmaceuticals. Chromatography is performed to Bondclow ODS column using a mobile phase coinsisting of acetonitrile-PIC B6 buffer, pH 4.75 (13:87) with ultraviolet wavelength at 220 nm. The linearity calibration range was 0.05 mg/ml to 2.5 mg/ml (r=0.9999), and recoveries were generally greater than 98.0%
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