“薑黃”為十分熱門之保健素材，有抗氧化、抗癌、抗阿茲海默症等許多保健功效。其主要活性物薑黃 素具有不耐pH與光等缺點，如何保護其不受外在環境破壞成為熱門研究方向。“流動床”造粒技術為微膠 囊粉粒重要製備技術之一，許多文獻指出操作條件對粉體品質有很大影響，如何改善造粒效果及品質亦是重 要待突破之技術。本研究以薑黃萃取液探討不同入風溫度 (Tinlet) 及噴霧流速 (Sr) 於造粒過程中黏著、包覆與 乾燥對品質及薑黃包覆率影響，結果如下：當Tinlet較高時其粉粒以70℃ 、流速10 rpm造粒180分鐘有最低Aw： 0.155。隨造粒時間增加L值下降，a、b值增加，Tinlet提高變化更顯著，粒徑分析隨造粒時間延長其粒徑之分佈 皆增大 (向右位移)，粒徑增長最快，且最大達330.62 μm，流動性試驗中可知經造粒後，粉體之流動性增加， 其中以60℃ 、7 rpm有最低CI% (Carr index)：10.91%及Hr：1.12，屬於流動性非常好之粉體，在熱分析中可以得 知Tg隨造粒時間增加，由包埋量分析中可知操作參數對於包埋量有顯著的影響，其中以70℃ 、7 rpm有較高的 包埋量0.477 mg/g ( p < 0.05)，由結果知操作參數對品質是非常重要的影響因子，考量包埋率、粉體品質可推測 60℃ 、7 rpm為較適條件；希盼本實驗結果能做為流動床包埋薑黃相關研究與產業生產時之參考，並為未來進 行多層次包埋奠定基礎。

“Turmeric” is a very popular healthy ingredient with many such health benefits as antioxidation, anticancer, anti-alzheimer’s disease. The main bioactive compound in turmeric is curcumin, which intolerance pH and light. There are popular research on how to protect it from external environment. Fluid bed agglomeration is an important microcapsulated powder produced technique. There were many literatures showed that operated parameters influenced on the quality of powders, deeply. How to improve the agglomerated effect and quality is an important unbreakthrough technology. In this study, we used turmeric extract as indicator to investigate the inlet air temperature(Tinlet) and spray rate(Sr) of binder, effected on quality and coating efficiency during adhesive, coating and dried. The experiment results were as follow: there was lowest water activity: 0.155, when agglomerated for 180 min under 70oC 10 rpm. The increased of agglomerated time followed by L value decreased and a,b value increased, and the change was more significant when Tinlet increased. The particle size distribution was increased (shifted to right) when agglomerated time increased, and the biggest was 330.62 μm. In flowability test, the powder flowability increased after agglomeration. Agglomeratd with 60oC 7 rpm had lowest CI% : 10.91% and Hr : 1.12, which flowability classified excellent. Tg was increased with agglomerated time, in thermal analyzed. We could know that operated parameters had significantly effect on coating efficiency. Among them agglomerated with 70oC 7 rpm had highest coating efficiency: 0.477 mg/g ( p < 0.05). This study proved that operated parameters was very important impact factor for quality. Considering coating efficiency, powder quality, 60oC 7 rpm was the best operating conditions. We hoped that the results of this study could apply and be a referenced on the related research and industrial production encapsulated turmeric by fluid bed technique. And laid the foundation on multiple layer encapsulated for the future.