篇名 | 三種台灣樹豆之體外抗氧化活性與對血糖調節酵素及蛋白質醣化反應的抑制作用 |
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卷期 | 55:2 |
並列篇名 | In vitro Antioxidation as Well as Inhibition of Hyperglycemic Regulated Enzymes and Protein Glycation of Three Taiwanese Pigeon Pea Species |
作者 | 高馥君 、 蘇正德 、 江文德 、 林筑盈 |
頁次 | 067-073 |
關鍵字 | 樹豆 、 類黃酮 、 血糖調節相關酵素 、 醛醣還原酶 、 最終醣化蛋白產物 、 Pigeon pea 、 Flavonoid 、 Hyperglycemic regulated enzymes 、 Aldose reductase 、 Advanced glycation end products 、 Scopus 、 TSCI |
出刊日期 | 201704 |
DOI | 10.6578/TJACFS.2017.007 |
樹豆在民俗療法中,常用於糖尿病、肝炎、麻疹、婦女生理期不適的醫治,含有豐富的多酚類化物與類黃酮,有益於人體健康。在台灣,目前已培育出產量高且品質穩定的三個樹豆新品種,分別命名為樹豆台東1號、樹豆台東2號、與樹豆台東3號。本研究中發現樹豆的乙醇萃取物中,以台東3號的總酚、總類黃酮含量與抗氧化活性最高;分別是264 mg GAE/g、87.9 mg QE/g、27.2 mg TEAC/g。在血糖調節相關酵素 (α-amylase、α-glucosidase) 抑制活性、醛醣還原酶抑制活性及最終醣化蛋白產物抑制形成活性上,也以樹豆台東3號最高,其IC50值分別為:268、110、126、與99.9 μg/mL,具有發展成血糖管理保健食品的潛力。
Pigeon pea [Cajanus cajan (L.) Millsp.], is used for treatment of diabetes, hepatitis, measles, and to stabilize the menstrual period in the traditional folk medication. Polyphenols, especially flavonoids, have been considered as being responsible for theses beneficial efficacies on the human health. In Taiwan, three new varieties of pigeon pea with high quality have been successfully bred, which were named as Pigeon pea Taitung No.1, 2 and 3, respectively. In the present study, the ethanol extract from pigeon pea Taitung No.3 exhibited the highest total phenolic content (264 mg GAE/g), total flavonoid content (87.9 mg QE/g), antioxidant activity (27.2 mg TEAC/g), in vitro hypoglycemic activities (α-amylase inhibition: IC50 = 268 μg/mL and α-glucosidase inhibition: IC50 = 110 μg/mL), aldose reductase inhibition activity (IC50 = 126 μg/mL) and has the ability to prevent the formation of advanced glycation end products (AGEs) (IC50 = 99.9 μg/mL). In conclusion, pigeon pea Taitung No.3 has the potential to be developed as an element in the management of hyperglycemia.