過去研究已經發現嚴謹性對病人安全有正向的影響力，但尚未有研究探討是否神經質會調節這樣的影 響力。若有研究探討此不足之處將可提供提升病人安全的方式。因此，本研究的目的為探討護理人員人格 特質中的嚴謹性與神經質的交互作用對病人安全的影響力。 本研究採用橫斷面的調查研究法，使用短題版的人格特質量表Mini-Markers，本研究的樣本為台灣的 兩家醫學中心中的313位護理人員。病人安全採用六種病人安全事件來衡量。採用迴歸分析來檢測研究假 說。本研究發現護理人員的嚴謹性與神經質的交互作用的確會對病人安全的結果有預測力（P = -.15 p =.01)。對於低神經質的護理人員，嚴謹性與病人安全有正向關係（P = .30, p = .00)。對於高神經質的護理 人員，嚴謹性與病人安全間的正向關係則不顯著（P = .11, p = .21)。 管理者可以提供訓練課程、放鬆課程、或者營造支持團體來逐漸增進護理人員的嚴謹性與降低神經質， 或有助於病人安全。管理者可考慮採取漸進提升護理人員嚴謹性與降低神經質外顯行為的方式，可能有助 於提升病人安全。

This study investigates the influence on patient safety of the interaction between nurse personality traits，i.e.， conscientiousness and neuroticism. Previous studies have identified the positive impact of conscientiousness on patient safety but little is known about how neuroticism moderates this impact. Research on this issue provides a means for enhancing patient safety. This study is a cross-sectional survey in which personality traits，i.e.，conscientiousness and neuroticism，are measured by items from Mini-Markers. The sample comprised 313 nurses from two medical centers in Taiwan. Patient safety outcomes were measured using frequencies of six adverse events. Regressions were used. Analytical results indicated that the effect of the interaction between nurse conscientiousness and neuroticism significantly predicts a range of patient safety outcomes 作=-.15, p = .01). For nurses with low neuroticism，conscientiousness was positively related to patient safety 作=.30, p = .00). For nurses with high neuroticism, the correlation between conscientiousness and patient safety was not observed (P = .11, p = .21). It is suggested that nursing managers increase nurse conscientiousness and decrease neuroticism to potentially improve patient safety. Nursing managers may provide training courses，relaxation courses，and support groups to gradually increase nurse conscientiousness and decrease nurse neuroticism to improve patient safety outcomes.