目前已知孕婦甲狀腺功能亢進對胎兒具有嚴重的不利影響。因此，如果可能，對甲狀腺 功能亢進(hyperthyroidism) 的孕婦應盡早治療，降低母體甲狀腺功能亢進對其本身以及對胎 兒的不良影響。對於治療藥物的選擇、開刀的適應症與時機，及131I 的輻射危害之了解是不 可或缺的。本文包含孕婦甲狀腺功能亢進，其檢驗判讀與診斷，對胎兒所造成的危害，以及 相關的治療。

It is well established that maternal hyperthyroidism has adverse effect on fetal development. Therefore it is important to treat maternal hyperthyroidism as early as possible in order to lower the risk of both mother and fetus. It is also necessary to understand the importance of the choice of antithyroid drug, timing and indication of operation, and the radiation danger of 131I. The aim of this article is to discuss the diagnosis and treatment of hyperthyroidism of the pregnant women and its adverse effect to the fetus. (J Intern Med Taiwan 2018; 29: 305-308)