目的：近年來肥胖已成為一個重要公衛議題，中心型肥胖更與心血管疾病、糖尿病、高血壓、高血脂及較高致死率相關。此外職業促發腦心血管疾病是近年來備受重視的職業病。本研究分析醫療從業人員體檢資料，了解中心型肥胖的盛行率及其相關健康風險。方法：本研究為橫斷性研究，分析2015至2019年北部某醫學中心員工之健檢資料，以男性腰圍90公分及女性腰圍80公分作為腹部肥胖切點。以描述統計分析基本資料、皮爾森相關係數衡量腰圍與心血管及代謝危險因子的相關性。最後以邏輯斯迴歸分析心血管及代謝危險因子的異常與中心型肥胖之關聯性。結果：共有9202位醫療從業人員納入統計分析，平均年齡41.94歲，男性31.13%及女性27.25%屬於中心型肥胖。年齡、血壓、身體質量指數、麩胺酸丙酮酸轉氨基酵素、肌酸酐、空腹血糖、血脂肪及尿酸在兩組中皆達顯著差異且相關。迴歸分析發現中心型肥胖者收縮壓、空腹血糖、麩胺酸丙酮酸轉氨基酵素、高密度脂蛋白膽固醇、三酸甘油脂及尿酸異常的勝算比皆達顯著。結論：醫療從業人員腰圍異常與血壓、麩胺酸丙酮酸轉氨基酵素、空腹血糖、低密度脂蛋白膽固醇、總膽固醇、三酸甘油脂及尿酸呈正相關，與高密度脂蛋白膽固醇呈負相關。故應透過腰圍量測篩檢出高危險群，做相關之健康風險評估及介入。

Background and purpose: Obesity had become an important public health problem. Central obesity is associated with an increased risk of cardiovascular disease, diabetes, hypertension, abnormal lipid profile, as well as mortality. Overwork-related cardiovascular and cerebrovascular diseases are common in Asia. The purpose of this study is to assess the prevalence of central obesity, correlation between central obesity and health risks in hospital employees. Methods: This cross-sectional study recruited hospital employees between 2015 and 2019.Central obesity is defined as waist circumference (WC) over 90cm for men or WC over 80 cm for women. Result: Among 9029 participants(aged 22-79years), the prevalence of central obesity were 31.13% in men and 27.25% in women. Age, blood pressure, body mass index(BMI), alanine aminotransferase( ALT), creatinine, fasting plasma glucose(FPG), lipid profile and uric acid(UA) were statistically significant difference between two groups, and correlated with WC. After adjusting for confounding factors, we found that the odds ratio for abnormality of systolic blood pressure(SBP), FPG, ALT, high density lipoprotein cholesterol(HDL-C), triglyceride(TG), and UA increased and reached statistically significant difference. Result: Central obesity was correlated with some health risks associated with cardiovascular disease in health care workers. The use of WC to screen health care workers at high risk for cardiovascular disease is important and convenient.