照顧者在整個機構照護體系扮演者重要的角色，其健康照護及用藥安全知能關係著身心障礙者的照護品質。本研究主要目的乃運用藥安全五大核心能力為基礎，藉以了解身心障礙機構的照顧者對於用藥安全識能的認知情形與分析其相關因素。本研究以橫斷性研究設計，利用結構性問卷評估機構照顧者的用藥安全識能。問卷主要內容以衛生福利部正確用藥五大核心能力原則，調查機構照顧者的用藥安全核心識能。研究對象為我國身心障礙機構工作人員9,214人為研究母群。經過樣本估計以立意取樣七家身心障礙福利機構共招募454照顧者為研究對象。問卷資料收集後，以SPSS 20.0版統計套裝軟體進行統計分析。研究結果顯示正確用藥五大核心能力識能的平均分數為79.7。經多變項分析指出，教育程度越高、有使用藥物或保健食品經驗者、身體感到不適時就選擇就醫者、固定醫療院所就醫及未重複就醫者，其用藥安全識能較佳。由本研究得知，機構照顧者的用藥安全識能情形尚可，建議機構可以定期舉辦用藥安全教育、提供衛教素材或建構線上學習系統，提升照顧者之用藥安全識能，以確保機構身心障礙者健康照護品質。

Institutional caregivers play a vital role on caring for people with disabilities. Knowledge and perception of medication safety of caregivers affect quality care of people with dsiabilities in institutional care. The present study aims to examine the perception and factors associated with medication safety literacy of caregiver working in disability welfare institutions. A cross-sectional study and a structured questionnaire were emplyes to recruit 454 caregivers from 7 disability institutions in the analysis. Results found that the average score of the five core competencies of medication safety literacy was 79.7. Analyzed by multivariate Analyses, this study indicated that factors of education, experience of using drugs or healthy food, medical visit at the right time, chosed regular medical setting, do not use redudent medical treatment, those caregivers have good perceptions on medication safety score. Based on the findings, the caregivers’ perceptions on medication safety are fair and needed to impove in the duture. This study highlights that the disability institutions should provide educations on medication safety, safety materials or e-learning classes, to increase caregivers’ literacy on medication safety to protect the quality care for people with disabilities.