背景與目的：過去研究心臟疾患之健康相關生活品質多聚焦於冠狀動脈繞道手術患者，且多數未採用針對特定疾病所設計之健康生活品質問卷，因此對於急性心肌梗塞後接受經皮冠狀動脈介入術患者之生活品質仍待研究探討。心臟復健是患者康復之路的重要一環，6分鐘行走測試及手握力是心臟復健常見之評估項目，若能了解6分鐘行走測試及手握力與生活品質之關聯，有助於物理治療師對於評估結果的解讀，以及介入計畫的擬定。因此，本研究目的為探討急性心肌梗塞接受經皮冠狀動脈介入術後，患者出院前之6分鐘行走測試及手握力表現與出院後2週及4週之生活品質關聯。方法：104位急性心肌梗塞接受經皮冠狀動脈介入術患者參與本研究，於出院前進行6分鐘行走測試及手握力評估，並於出院後2週及4週接受麥紐心臟疾病健康相關生活品質問卷評量。以皮爾森相關分析受試者出院前6分鐘行走距離及手握力與出院後生活品質之相關，並以逐步迴歸統計分析探討生活品質預測因子。結果：6分鐘行走距離及手握力與2週及4週生活品質總分、身體、情緒及社會面向皆具顯著正相關(r=0.58~0.77, p<0.05)，且兩者皆為生活品質總分之預測因子，但以6分鐘行走距離解釋力較高。結論：急性心肌梗塞接受經皮冠狀動脈介入術後患者之健康相關生活品質逐漸提升，6分鐘行走距離及手握力可預測患者術後之生活品質，但心肺耐力是患者健康相關生活品質之較為主要的決定因子。

Background and Purpose: Previous studies on the health-related quality of life of heart diseases focused on patients after coronary artery bypass surgery, and most of them did not use a disease-specific quality of life questionnaire. Therefore, the quality of life of patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) remains to be studied. Cardiac rehabilitation plays an important role in the patient’s recovery. The 6-minute walk test and handgrip strength are common assessment items for cardiac rehabilitation. Understanding the relationship between the 6-minute walk test and handgrip strength and quality of life will help physical therapists interpret the evaluation results and design appropriate intervention plans. Therefore, the purpose of this study was to explore the relationship between the 6-minute walk test and handgrip of patients with AMI after PCI before discharge and the quality of life in the 2 and 4 weeks after discharge. Methods: One hundred and four patients with AMI after PCI participated in this study. The six-minute walk test and handgrip assessments were given at discharge from the hospital, and MacNew Heart Disease health-related quality of life questionnaire was used to evaluate quality of life 2 weeks and 4 weeks after discharge. Pearson’s correlation analysis was used to analyze the correlation between the walking distance and handgrip strength and quality of life. Stepwise regression analysis was used to explore the predictive factors of quality of life. Results: Significant positive correlations (r = 0.58 ~ 0.77, p < 0.05) were found between walking distance and handgrip strength and the total scores of quality of life as well as physical, emotional, and social aspects for 2 weeks and 4 weeks. Walking distance and handgrip strength were the predictive factors of the total score of quality of life, but the explanatory power was higher with the walking distance. Conclusion: The health-related quality of life of individuals with AMI after PCI is gradually improved. The 6-minute walking distance and handgrip strength can predict the quality of life of patients after surgery, but cardiopulmonary endurance is the main determinant of the quality of life.