國際原子能總署(International Atomic Energy Agency, IAEA)劑量實驗室(Dosimetry Laboratory, DOL)提供高能光子射束獨立的遠端輻射度量，來改善全球醫院臨床劑量的準確性。熱發光劑量(Thermoluminescent Dosimetry, TLD)系統提供全球輻射度量服務超過47年。光激發光劑量(Optically Stimulated Luminescent Dosimetry, OSLD)為新的輻射度量系統，本研究對系統參數、計讀方法和劑量特性進行研究和比較。建立並優化每個系統的計讀程序，例如劑量特性、再現性、消光效應、劑量訊號依賴性和能量依存性。透過對OSLD進行額外測試，以檢查每個計讀的訊號損耗以及劑量計的個別靈敏度。研究結果顯示之TLDs再現性為0.46%，OSLDs為0.13%。100天後TLD的消光效應為5%，OSLD為3%。TLD計讀過程具有破壞性，但OSLDs可以重複計讀，且OSLDs的每次計讀訊號損耗為0.032%。OSLDs的靈敏度校正因子(Sensitivity Correction Factors, SCFs)是通過1000個劑量計反應的標準偏差確定為2.1%。組合標準不確定度（k=1），對於TLDs為1.58%，對於OSLDs為1.43%。研究成果可提供給臨床使用兩種劑量計進行輻射度量之參考。

The IAEA Dosimetry Laboratory (DOL) aims to improve the accuracy of clinical dosimetry in hospitals world-wide. A thermoluminescent dosimetry (TLD) system has been provided dosimetry services for over 47 years. Optically Stimulated Luminescence (OSL) has become the technique of choice for many areas of radiation dosimetry. The systems’ parameters, reading methodology and the dosimetric characteristics were investigated and compared. The read-out procedure for each system was established and optimized. Dosimetric characteristics such as reproducibility, signal fading with time after irradiation, signal per dose dependence and energy response were investigated. Additional tests to check signal depletion per readout and individual sensitivities of dosimeters were performed for TLDs and OSLDs and also reading position dependence for the OSLD system was checked. The reproducibility of 4 readings of one dosimeter is 0.42% for TLDs and 0.13% for OSLDs. The fading effect after 100 days was 5% for TLD and 3% for OSLD. The TLD reading procedure is destructive but OSLDs can be read repeatedly and the signal depletion per reading is 0.032% for OSLDs. The sensitivity correction factors for OSLDs were determined with the standard deviation in response of 1000 dosimeters of 2.1% for OSLD. The combined standard uncertainties (k = 1) are 1.58% for TLDs, 1.43% for OSLDs. This research can be provided for clinical reference.